Triterpene saponins from the roots of Parkia bicolor A. Chev

被引：7

作者：

Bitchi, Michel Boni ^{[1
,2
]}

Magid, Abdulmagid Alabdul ^{[1
]}

Yao-Kouassi, Philomene Akoua ^{[2
]}

Kabran, Faustin Aka ^{[2
]}

Harakat, Dominique ^{[1
]}

Martinez, Agathe ^{[1
]}

Morjani, Hamid ^{[3
]}

Tonzibo, Felix Zanahi ^{[2
]}

Voutquenne-Nazabadioko, Laurence ^{[1
]}

机构：

[1] Univ Reims, CNRS, ICMR UMR 7312, F-51097 Reims, France

[2] Univ Felix Houphouet Boigny, Lab Chim Organ Biol, UFR Sci Struct Mat & Technol, 22 BP 582, Abidjan 22, Cote Ivoire

[3] Univ Reims, BioSpect EA 7506, F-51097 Reims, France

来源：

FITOTERAPIA | 2019年 / 137卷

关键词：

Parkia bicolor; Fabaceae; Triterpenoid saponins; Diterpene; Cytotoxic activity; BARK; CONSTITUENTS; GLYCOSIDES; BIGLOBOSA;

D O I：

10.1016/j.fitote.2019.104264

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Five undescribed triterpene-type saponins, parkibicolorosides A-E, a cassane-type diterpene, and a known trimethoxy benzene glucoside were isolated from the roots of Parkia bicolor A. Chev. Their structures were elucidated by different spectroscopic methods including 1D- and 2D-NMR experiments as well as HR-ESI-MS analysis. Their cytotoxic activity against the chronic myeloid leukemia (K562) cell line was evaluated. The monosaccharides saponins exhibited a moderate antiproliferative activity with IC50 ranging from 48.49 +/- 0.16 to 81.66 +/- 0.17 mu M.

引用

页数：8

共 50 条

[1] Two new steroidal saponins from the roots of Cordyline fruticosa (L.) A. Chev
Thi Hai Yen Nguyen
Hoang Mau Chu
Duc Hung Nguyen
[J]. NATURAL PRODUCT RESEARCH, 2024, 38 (07) : 1191 - 1196
[2] Triterpene saponins from the roots of Achyranthes bidentata
Marouf, A
Desbene, S
Khanh, TC
Wagner, H
Correia, M
Chauffert, B
Lacaille-Dubois, MA
[J]. PHARMACEUTICAL BIOLOGY, 2001, 39 (04) : 263 - 267
[3] Triterpene saponins from the roots of Medicago hybrida
Bialy, Z
Jurzysta, M
Mella, M
Tava, A
[J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2006, 54 (07) : 2520 - 2526
[4] Triterpene saponins from the roots of Ilex pubescens
Zhou, Yuan
Zeng, Kewu
Zhang, Jiayu
Li, Ning
Chai, Xingyun
Jiang, Yong
Tu, Pengfei
[J]. FITOTERAPIA, 2014, 97 : 98 - 104
[5] Triterpene saponins from the roots of Clematis chinensis
Mimaki, Y
Yokosuka, A
Hamanaka, M
Sakuma, C
Yamori, T
Sashida, Y
[J]. JOURNAL OF NATURAL PRODUCTS, 2004, 67 (09): : 1511 - 1516
[6] Triterpene Saponins from the Roots of Ilex asprella
Lei, Yu
Shi, She-Po
Song, Yue-Lin
Bi, Dan
Tu, Peng-Fei
[J]. CHEMISTRY & BIODIVERSITY, 2014, 11 (05) : 767 - 775
[7] Oleanolic Triterpene Saponins from the Roots of Panax bipinnatifidus
Nguyen Huu Tung
Tran Hong Quang
Nguyen Thi Thanh Ngan
Chau Van Minh
Bui Kim Anh
Pham Quoc Long
Nguyen Manh Cuong
Kim, Young Ho
[J]. CHEMICAL & PHARMACEUTICAL BULLETIN, 2011, 59 (11) : 1417 - 1420
[8] Cycloartane triterpene saponins from the roots of Cimicifuga foetida
Zhu, NQ
Jiang, Y
Wang, MF
Ho, CT
[J]. JOURNAL OF NATURAL PRODUCTS, 2001, 64 (05): : 627 - 629
[9] Acylated triterpene saponins from the roots of Securidaca longepedunculata
Mitaine-Offer, Anne-Claire
Penez, Nicolas
Miyamoto, Tomofumi
Delaude, Clement
Mirjolet, Jean-Francois
Duchamp, Olivier
Lacaille-Dubois, Marie-Aleth
[J]. PHYTOCHEMISTRY, 2010, 71 (01) : 90 - 94
[10] Triterpene saponins from the roots of Bupleurum spinosum Gouan
Dahmoune, Amina
Smati, Dalila
Mitaine-Offer, Anne-Claire
Miyamoto, Tomofumi
Tanaka, Chiaki
Paululat, Thomas
Lacaille-Dubois, Marie-Aleth
[J]. PHYTOCHEMISTRY LETTERS, 2020, 39 : 157 - 161

← 1 2 3 4 5 →