Deciphering metabolic remodeling of the failing hearts

被引：2
|
作者：
Yoshii, Akira [1 ]
Tian, Rong [1 ]
机构：
[1] Univ Washington, Mitochondria & Metab Ctr, Seattle, WA 98109 USA
来源：
NATURE CARDIOVASCULAR RESEARCH | 2022年 / 1卷 / 09期
关键词：
ENERGY-METABOLISM;
D O I：
10.1038/s44161-022-00118-5
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A landscape view of metabolic remodeling in end-stage human failing hearts generated by multiomics analysis confirms main changes in cardiac energy metabolism and challenges several widely held mechanisms derived from animal models. Further validation in non-end-stage heart failure and metabolic flux analysis will be necessary to move the field forward.
引用
收藏
页码：800 / 801
页数：2
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