Phase I pharmacokinetic, and pharmacodynamic trial of the novel oral notch inhibitor MK-0752 in patients with advanced breast cancer and other solid tumors.

被引:0
|
作者
Krop, I. E.
Kosh, M.
Fearen, I
Savoie, J.
Dallob, A.
Stone, J.
Winer, E.
Freedman, S. J.
LoRusso, P.
机构
[1] Dana Farber Canc Inst, Boston, MA 02115 USA
[2] Merck Res Labs, N Wales, PA USA
[3] Barbara Ann Karmanos Canc Inst, Detroit, MI USA
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:S287 / S287
页数:1
相关论文
共 50 条
  • [21] Phase I Pharmacokinetic and Pharmacodynamic Study of the Aurora Kinase Inhibitor Danusertib in Patients With Advanced or Metastatic Solid Tumors
    Steeghs, Neeltje
    Eskens, Ferry A. L. M.
    Gelderblom, Hans
    Verweij, Jaap
    Nortier, Johan W. R.
    Ouwerkerk, Jan
    van Noort, Conny
    Mariani, Mariangela
    Spinelli, Riccardo
    Carpinelli, Patrizia
    Laffranchi, Bernard
    de Jonge, Maja J. A.
    JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (30) : 5094 - 5101
  • [22] Phase I trial of irinotecan and epirubicin in patients with advanced solid tumors.
    Gold, PJ
    Refice, S
    West, H
    JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (16) : 164S - 164S
  • [23] Phase I trial of SU011248, a novel tyrosine kinase inhibitor in advanced solid tumors.
    Rosen, L
    Mulay, M
    Long, J
    Wittner, J
    Brown, J
    Martino, AM
    Bello, CL
    Walter, S
    Scigalla, P
    Zhu, J
    JOURNAL OF CLINICAL ONCOLOGY, 2003, 21 (23) : 284S - 284S
  • [24] A phase I pharmacokinetic and pharmacodynamic study of intravenous calcitriol in combination with oral gefitinib in patients with advanced solid tumors
    Fakih, Marwan G.
    Trump, Donald L.
    Muindi, Josephia R.
    Black, Jennifer D.
    Bernardi, Ronald J.
    Creaven, Patrick J.
    Schwartz, James
    Brattain, Michael G.
    French, Renee
    Johnson, Candance S.
    CLINICAL CANCER RESEARCH, 2007, 13 (04) : 1216 - 1223
  • [25] Phase I, dose-escalation, safety, pharmacokinetic, and pharmacodynamic study of single-agent PF-03758309, an oral PAK inhibitor, in patients with advanced solid tumors.
    Mileshkin, L. R.
    Rosen, L. S.
    Blumenkopf, T.
    Breazna, A.
    Darang, S.
    Davison, J.
    Gallo, J.
    Goldman, J. W.
    Wang, D. D.
    Zhang, S.
    Eckhardt, S. G.
    JOURNAL OF CLINICAL ONCOLOGY, 2011, 29 (15)
  • [26] Phase I study of CFI-402257, an oral TTK inhibitor, in patients with advanced solid tumors.
    Cescon, David W.
    Hansen, Aaron Richard
    Razak, Albiruni Ryan Abdul
    Stayner, Lee-Anne
    Hilton, John Frederick
    Renouf, Daniel John
    Denny, Trisha
    Fletcher, Graham
    Mak, Tak W.
    Bray, Mark R.
    Bedard, Philippe L.
    JOURNAL OF CLINICAL ONCOLOGY, 2017, 35
  • [27] A phase I pharmacokinetic and pharmacodynamic study of S-3304, a novel matrix metalloproteinase inhibitor, in patients with advanced and refractory solid tumors
    Chiappori, Alberto A.
    Eckhardt, S. Gail
    Bukowski, Ronald
    Sullivan, Daniel M.
    Ikeda, Minoru
    Yano, Yoshitaka
    Yamada-Sawada, Takuko
    Kambayashi, Yoshikaze
    Tanaka, Kazushige
    Javle, Milind M.
    Mekhail, Tarek
    O'Bryant, Cindy L.
    Creaven, Patrick J.
    CLINICAL CANCER RESEARCH, 2007, 13 (07) : 2091 - 2099
  • [28] A phase I pharmacokinetic and pharmacodynamic study of PX-12, a novel inhibitor of thioredoxin-1, in patients with advanced solid tumors
    Ramanathan, Ramesh K.
    Kirkpatrick, D. Lynn
    Belani, Chandra P.
    Friedland, David
    Green, Sylvan B.
    Chow, H-H. Sherry
    Cordova, Catherine A.
    Stratton, Steven P.
    Sharlow, Elizabeth R.
    Baker, Amanda
    Dragovich, Tomislav
    CLINICAL CANCER RESEARCH, 2007, 13 (07) : 2109 - 2114
  • [29] A phase I, pharmacokinetic and pharmacodynamic study of nimotuzumab in Japanese patients with advanced solid tumors
    Wataru Okamoto
    Takayuki Yoshino
    Toshiaki Takahashi
    Isamu Okamoto
    Shinya Ueda
    Asuka Tsuya
    Narikazu Boku
    Kazuto Nishio
    Masahiro Fukuoka
    Nobuyuki Yamamoto
    Kazuhiko Nakagawa
    Cancer Chemotherapy and Pharmacology, 2013, 72 : 1063 - 1071
  • [30] A phase I, pharmacokinetic and pharmacodynamic study of nimotuzumab in Japanese patients with advanced solid tumors
    Okamoto, Wataru
    Yoshino, Takayuki
    Takahashi, Toshiaki
    Okamoto, Isamu
    Ueda, Shinya
    Tsuya, Asuka
    Boku, Narikazu
    Nishio, Kazuto
    Fukuoka, Masahiro
    Yamamoto, Nobuyuki
    Nakagawa, Kazuhiko
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2013, 72 (05) : 1063 - 1071