Immune responses in Anopheles gambiae

被引:51
|
作者
Levashina, EA [1 ]
机构
[1] CNRS, Inst Biol Mol & Cellulaire, UPR 9022, F-67084 Strasbourg, France
关键词
Anopheles; Aedes; Plasmodium; mosquito immune response; antimicrobial peptides; hemocytes;
D O I
10.1016/j.ibmb.2004.03.020
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Transmission of human malaria requires a successful development of Plasmodium parasites in anopheline mosquitoes. Insects have developed efficient immune responses to oppose microbial and eukaryotic invaders. The completion of the sequencing of the Anopheles genome provides a wealth of information on putative immune genes that are homologous to components of the Drosophila and mammalian immune systems. In this review, we will summarize our present knowledge of immune responses in the mosquito Anopheles gambiae and attempt a comparative analysis of insect immune systems. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码:673 / 678
页数:6
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