Purpose of review The purpose is to review the development and current application of extracorporeal life support [ECLS, extracorporeal membrane oxygenation (ECMO)] in acute severe respiratory failure. Recent findings Extracorporeal support (ECMO) is used for acute severe respiratory failure in advanced ICUs. The current survival rate is 60-70%. Three controlled trials all demonstrated 20-30% improvement in survival compared to conventional care. Patients may now be maintained awake and ambulatory with spontaneous breathing. Summary ECMO is the next step in the algorithm for management of severe respiratory failure unresponsive to conventional care.
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Childrens Hosp Philadelphia, Div Neonatol, Philadelphia, PA 19104 USAChildrens Hosp Philadelphia, Div Neonatol, Philadelphia, PA 19104 USA
Bamat, Nicolas A.
Tharakan, Sasha J.
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Childrens Hosp Philadelphia, Div Gen Thorac & Fetal Surg, Philadelphia, PA 19104 USA
Univ Childrens Hosp Zurich, Gen & Thorac Surg, Zurich, SwitzerlandChildrens Hosp Philadelphia, Div Neonatol, Philadelphia, PA 19104 USA
Tharakan, Sasha J.
Connelly, James T.
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Childrens Hosp Philadelphia, Extracorporeal Membrane Oxygenat ECMO Ctr, Philadelphia, PA 19104 USAChildrens Hosp Philadelphia, Div Neonatol, Philadelphia, PA 19104 USA
Connelly, James T.
Hedrick, Holly L.
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Childrens Hosp Philadelphia, Div Gen Thorac & Fetal Surg, Philadelphia, PA 19104 USAChildrens Hosp Philadelphia, Div Neonatol, Philadelphia, PA 19104 USA
Hedrick, Holly L.
Lorch, Scott A.
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Childrens Hosp Philadelphia, Div Neonatol, Philadelphia, PA 19104 USAChildrens Hosp Philadelphia, Div Neonatol, Philadelphia, PA 19104 USA
Lorch, Scott A.
Rintoul, Natalie E.
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Childrens Hosp Philadelphia, Div Neonatol, Philadelphia, PA 19104 USAChildrens Hosp Philadelphia, Div Neonatol, Philadelphia, PA 19104 USA
Rintoul, Natalie E.
Williams, Susan B.
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Childrens Hosp Philadelphia, Extracorporeal Membrane Oxygenat ECMO Ctr, Philadelphia, PA 19104 USAChildrens Hosp Philadelphia, Div Neonatol, Philadelphia, PA 19104 USA
Williams, Susan B.
Dysart, Kevin C.
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Childrens Hosp Philadelphia, Div Neonatol, Philadelphia, PA 19104 USAChildrens Hosp Philadelphia, Div Neonatol, Philadelphia, PA 19104 USA
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Childrens Hosp Orange Cty, Dept Pediat, Div Crit Care, Orange, CA 92668 USAChildrens Hosp Orange Cty, Dept Pediat, Div Crit Care, Orange, CA 92668 USA
Domico, Michele B.
Ridout, Deborah A.
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UCL Inst Child Hlth, Ctr Paediat Epidemiol & Biostat, London, EnglandChildrens Hosp Orange Cty, Dept Pediat, Div Crit Care, Orange, CA 92668 USA
Ridout, Deborah A.
Bronicki, Ronald
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Childrens Hosp Orange Cty, Dept Pediat, Div Crit Care, Orange, CA 92668 USAChildrens Hosp Orange Cty, Dept Pediat, Div Crit Care, Orange, CA 92668 USA
Bronicki, Ronald
Anas, Nick G.
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Childrens Hosp Orange Cty, Dept Pediat, Div Crit Care, Orange, CA 92668 USAChildrens Hosp Orange Cty, Dept Pediat, Div Crit Care, Orange, CA 92668 USA
Anas, Nick G.
Cleary, John Patrick
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机构:Childrens Hosp Orange Cty, Dept Pediat, Div Crit Care, Orange, CA 92668 USA
Cleary, John Patrick
Cappon, James
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Childrens Hosp Orange Cty, Dept Pediat, Div Crit Care, Orange, CA 92668 USAChildrens Hosp Orange Cty, Dept Pediat, Div Crit Care, Orange, CA 92668 USA
Cappon, James
Goldman, Allan P.
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Great Ormond St Hosp Sick Children, Cardiac Intens Care Unit, London WC1N 3JH, EnglandChildrens Hosp Orange Cty, Dept Pediat, Div Crit Care, Orange, CA 92668 USA
Goldman, Allan P.
Brown, Katherine L.
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Great Ormond St Hosp Sick Children, Cardiac Intens Care Unit, London WC1N 3JH, EnglandChildrens Hosp Orange Cty, Dept Pediat, Div Crit Care, Orange, CA 92668 USA
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Univ Paris 06, Hop Pitie Salpetriere, AP HP, Serv Reanimat Med, F-75651 Paris 13, FranceUniv Paris 06, Hop Pitie Salpetriere, AP HP, Serv Reanimat Med, F-75651 Paris 13, France
Combes, Alain
Bacchetta, Matthew
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New York Presbyterian Hosp, Columbia Coll Phys & Surg, New York, NY USAUniv Paris 06, Hop Pitie Salpetriere, AP HP, Serv Reanimat Med, F-75651 Paris 13, France
Bacchetta, Matthew
Brodie, Daniel
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New York Presbyterian Hosp, Columbia Coll Phys & Surg, New York, NY USAUniv Paris 06, Hop Pitie Salpetriere, AP HP, Serv Reanimat Med, F-75651 Paris 13, France
Brodie, Daniel
Mueller, Thomas
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Univ Med Ctr Regensburg, Dept Med, Regensburg, GermanyUniv Paris 06, Hop Pitie Salpetriere, AP HP, Serv Reanimat Med, F-75651 Paris 13, France
Mueller, Thomas
Pellegrino, Vince
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Monash Univ, Melbourne, Vic 3004, Australia
Alfred Hosp, Melbourne, Vic, AustraliaUniv Paris 06, Hop Pitie Salpetriere, AP HP, Serv Reanimat Med, F-75651 Paris 13, France
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Hosp Univ Rio Hortega, Serv Med Intens, Gerencia Reg Salud Castilla & Leon SACYL, Calle Dulzaina 2, Valladolid 47012, SpainAlma Mater Studiorum Univ Bologna, Dept Med & Surg Sci DIMEC, Bologna, Italy
Perez-Torres, David
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Grasselli, Giacomo
Ranieri, V. Marco
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Alma Mater Studiorum Univ Bologna, Dept Med & Surg Sci DIMEC, Bologna, Italy
IRCCS Azienda Osped Univ Bologna, Policlin S Orsola, Anesthesiol & Gen Intens Care Unit, Bologna, ItalyAlma Mater Studiorum Univ Bologna, Dept Med & Surg Sci DIMEC, Bologna, Italy