Natural and Synthetic Compounds with an Antimycobacterial Activity

This review discusses the most active natural and synthetic compounds demonstrating the antimycobacterial activity at minimum inhibiting concentrations (MIC) of 5 mu g/ml or less. For better insight into the "structure-activity" relationships, we occasionally considered compounds with high values of MIC. The review covers the period from 2001 to 2007. The data are grouped according to chemical structures, namely, nitrogen-, oxygen-, and sulfur-containing heterocyclic compounds, peptide, alkaloids, terpenoids, and others.