Granulomatosis with polyangiitis presenting with pachymeningitis

被引：5
|
作者：
Onyeuku, Nasarachi E. [1 ]
Balakrishnan, Nikhil [2 ]
Cartwright, Michael S. [2 ]
机构：
[1] Wake Forest Sch Med, Winston Salem, NC USA
[2] Wake Forest Sch Med, Dept Neurol, Winston Salem, NC 27157 USA
来源：
JOURNAL OF THE NEUROLOGICAL SCIENCES | 2014年 / 344卷 / 1-2期
关键词：
Granulomatosis with polyangiitis; Wegener's granulomatosis; Pachymeningitis; Headache; MRI; Cranial neuropathy;
D O I：
10.1016/j.jns.2014.06.052
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Observations: This case report describes a 75 year-old Caucasian male who initially presented with persistent daily headaches. Physical exam elicited multiple cranial nerve palsies. Gadolinium-enhanced brain MRI demonstrated pachymeningitis. Labs revealed elevated proteinase-3 antineutrophil cytoplasmic antibodies (PR3-ANCA) and cytoplasmic antineutrophil cytoplasmic antibodies (c-ANCA), confirming a diagnosis of CPA. Conclusion: GPA should be considered in older patients presenting with persistent daily headaches and pachymeningitis. Contrast-enhanced brain MRI is an important diagnostic tool. (C) 2014 Elsevier B.V. All rights reserved.
引用
收藏
页码：208 / 209
页数：2
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