Rituximab for treatment of pachymeningitis in granulomatosis with polyangiitis

被引：0
|
作者：
Patankar, Aditi [1 ]
Yadav, Sandeep [1 ]
Balakrishnan, Canchi [1 ]
Baliga, Sahana [1 ]
机构：
[1] PD Hinduja Natl Hosp & Med Res Ctr, Rheumatol, Mumbai, Maharashtra, India
来源：
BMJ CASE REPORTS | 2023年 / 16卷 / 07期
关键词：
Cryptococcosis; Vasculitis; Biological agents; NERVOUS-SYSTEM INVOLVEMENT; ANCA-ASSOCIATED VASCULITIS; HYPERTROPHIC PACHYMENINGITIS; WEGENERS-GRANULOMATOSIS; MANIFESTATION; THERAPY;
D O I：
10.1136/bcr-2022-253835
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Pachymeningitis is a rare manifestation of granulomatosis with polyangiitis (GPA), and there is a paucity of literature regarding the efficiency of rituximab (RTX) in such cases. We present a woman in her early 50s with GPA who initially responded adequately to conventional therapy. However, the treatment course was complicated by pulmonary cryptococcosis. The patient later developed non-infectious pachymeningitis, which failed to respond to steroids and methotrexate. However, using RTX upfront led to good clinical response and radiological resolution.
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页数：6
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