The prevalence and pattern of neural tube defects and other major congenital malformations of nervous system detected at birth in Barbados

被引:3
|
作者
Singh, Keerti [1 ]
Johnson, W. M. S. [2 ]
Archana, R. [2 ]
Kumar, Alok [1 ,3 ]
机构
[1] Univ West Indies, Fac Med Sci, Cave Hill, Bridgetown, Barbados
[2] Sree Balaji Med Coll & Hosp, BIHER, Dept Anat, Madras 44, Tamil Nadu, India
[3] Queen Elizabeth Hosp, Bridgetown, Barbados
关键词
Caribbean; Congenital malformation; Nervous system; Prevalence; Neural tube defects; FOLIC-ACID FORTIFICATION; ABNORMALITIES; PREGNANCIES;
D O I
10.1016/j.jasi.2016.08.001
中图分类号
R602 [外科病理学、解剖学]; R32 [人体形态学];
学科分类号
100101 ;
摘要
Introduction: Neural tube defects are the commonest major congenital malformation of nervous system. There is paucity of published data on the public health burden of major congenital malformations from the English Caribbean. The objective of this study was to describe the prevalence and pattern of major congenital malformations of the nervous system seen at birth. We also describe the burden of neonatal morbidity and mortality from the neural defects. Material and methods: This was a retrospective clinical audit of all babies born with major congenital malformations of the nervous system in Barbados. The period of reporting was from 1993 to 2012. Relevant data on the babies with major congenital malformations of the nervous system were obtained from the birth register in the labor ward and the admissions register at the NICU. Result: The prevalence rate for neural tube defects, congenital hydrocephalus, and other Major Congenital Malformations of the Nervous System was 3.76, 2.66, and 1.25 per 10,000 live births, respectively. Major congenital malformations of nervous system accounted for 10 (1.6%; 95% CI = 0.8%-3.1%) deaths. The prevalence rate of neural tube defects is lower than those reported from most of the countries around the world. (C) 2016 Anatomical Society of India. Published by Elsevier, a division of RELX India, Pvt. Ltd. All rights reserved.
引用
收藏
页码:S20 / S24
页数:5
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