Evaluation of immunostaining of tumor stem cells in mammary carcinosarcomas and carcinomas in mixed tumors in bitches

被引：0

作者：

Magalhaes, Georgia M. ^{[1
]}

Terra, Erika M. ^{[2
]}

Calazans, Sabryna G. ^{[1
]}

Vasconcelos, Rosemeri de O. ^{[2
]}

Alessi, Antonio Carlos ^{[2
]}

机构：

[1] Univ Franca, Hosp Vet, BR-14404600 Franca, Brazil

[2] Univ Estadual Paulista Unesp, Fac Ciencias Agr & Vet, Dept Patol Vet, BR-14884900 Jaboticabal, Brazil

来源：

PESQUISA VETERINARIA BRASILEIRA | 2014年 / 34卷 / 05期

关键词：

CD44; CD24; Oct-4; ALDH-1; mammary neoplasms; diseases of dogs; BREAST-CANCER; IDENTIFICATION; MARKER;

D O I：

10.1590/S0100-736X2014000500012

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Cancer stem cells belong to a small population of cells within the tumor with properties of self-renewal and differentiation into other cell types. In this study, the behavior of both portions, mesenchymal and epithelial, was evaluated. Six carcinosarcomas (CSs), 11 carcinomas within mixed tumors (CWMTs) grade I, 11 grade II, and 10 grade III were evaluated. In the epithelial portions of the CS and CWMTs was observed immunostaining for antibodies CD44, CD24, Oct-4 and ALDH-1. In the mesenchymal portions of the CS, in the epithelial portions of CMTs grades II and III no immunostaining for ALDH-1 was found. It was concluded that the tumor stem cells are expressed in equal proportions in the epithelial and mesenchymal portions of the CS. No immunostaining in the mesenchymal portions of well-differentiated CWMTs was seen.

引用

页码：455 / 461

页数：7

共 50 条

[1] Evaluation of an immunohistochemical technique for the diagnosis of mixed mammary tumors in bitches
Evaluación de una técnica inmunohistoquímica para el diagnóstico de neoplasias mamarias mixtas en caninos
1600, Universidad Nacional Mayor de San Marcos (24):
[2] Ultrasonographic Evaluation of Mammary Tumors in Bitches
Bastan, Ayhan
Ozenc, Erhan
Yagci, Ilknur Pir
Acar, Duygu Baki
KAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI, 2009, 15 (01) : 81 - 86
[3] Uterine carcinosarcomas (malignant mixed Mullerian tumors) are metaplastic carcinomas
McCluggage, WG
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2002, 12 (06) : 687 - 690
[4] The Importance of Ultrasonography in the Evaluation of Mammary Tumors in Bitches
Feliciano, Marcus Antonio Rossi
de Miranda, Brenda dos Santos Pompeu
Aires, Luiz Paulo Nogueira
Lima, Bruna Bressianini
de Oliveira, Ana Paula Luiz
Feliciano, Giovanna Serpa Maciel
Uscategui, Ricardo Andres Ramirez
ANIMALS, 2023, 13 (11):
[5] Versican expression in myoepithelial cells from carcinomas in canine mixed mammary tumors
Damasceno, Karine A.
Bertagnolli, Angelica C.
Estrela-Lima, Alessandra
Rabelo, Bruna S.
Campos, Liliane C.
Ribeiro, Lorena G. R.
Cassali, Geovanni D.
VETERINARY JOURNAL, 2014, 200 (01): : 146 - 151
[6] ULTRASTRUCTURE OF MIXED MAMMARY-GLAND TUMORS IN BITCHES .4. INCIDENCE OF MYOEPITHELIAL CELLS IN FORMATIONS OF SPINDLE CELLS
BOMHARD, DV
SANDERSLEBEN, JV
VIRCHOWS ARCHIV A-PATHOLOGICAL ANATOMY AND HISTOPATHOLOGY, 1976, 371 (03) : 219 - 226
[7] ULTRASTRUCTURE OF MIXED MAMMARY-GLAND TUMORS IN BITCHES .2. INCIDENCE OF MYOEPITHELIAL CELLS IN CHONDROID AREAS
BOMHARD, DV
SANDERSLEBEN, JV
VIRCHOWS ARCHIV ABTEILUNG A PATHOLOGISCHE ANATOMIE, 1974, 362 (02): : 157 - 167
[8] ULTRASTRUCTURE OF MIXED MAMMARY-GLAND TUMORS IN BITCHES .1. INCIDENCE OF MYOEPITHELIAL CELLS IN MYXOID AREAS
BOMHARD, DV
SANDERSLEBEN, JV
VIRCHOWS ARCHIV ABTEILUNG A PATHOLOGISCHE ANATOMIE, 1973, 359 (01): : 87 - 96
[9] ULTRASTRUCTURE OF MIXED MAMMARY-GLAND TUMORS IN BITCHES .3. EARLY STAGES OF MYOEPITHELIAL PROLIFERATION
BOMHARD, DV
SANDERSLEBEN, JV
VIRCHOWS ARCHIV A-PATHOLOGICAL ANATOMY AND HISTOPATHOLOGY, 1975, 367 (03) : 219 - 229
[10] Evaluation of myeloid metaplasia in canine mixed mammary tumors
Cecilia B Campos
Patricia A Auler
Angelica C Bertagnolli
Enio Ferreira
Gustavo M Ribeiro
Ana PM Dias
Liliane C Campos
Geovanni D Cassali
BMC Proceedings, 7 (Suppl 2)

← 1 2 3 4 5 →