Cycloaddition reactions for the synthesis of piperidine and indolizidine alkaloids

被引：31
|
作者：
Holmes, AB
Bourdin, B
Collins, I
Davison, EC
Rudge, AJ
Stork, TC
Warner, JA
机构：
[1] University Chemical Laboratory, Cambridge CB2 1EW, Lensfield Road
来源：
PURE AND APPLIED CHEMISTRY | 1997年 / 69卷 / 03期
基金：
英国工程与自然科学研究理事会;
关键词：
D O I：
10.1351/pac199769030531
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The intramolecular nitrone dipolar cycloaddition of N-alkenylnitrone has been utilised in approaches to the synthesis of a family of indolizidines such as castanospermine and a tethered swainsonine analogue. Examples of a tandem hydroxylamino-alkyne cyclisation/dipolar trapping experiment in the synthesis of (+/-)-adaline and (+/-)-euphococcinine are outlined.
引用
收藏
页码：531 / 536
页数：6
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