Degradation of the neolignan, burchellin in the hemolymph of the bloodsucking insect Rhodnius prolixus

被引：1
|
作者：
Cabral, Marise M. O. [1 ,2 ]
Garcia, Eloi S. [3 ]
Gottlieb, Otto R. [4 ]
Kelecom, Alphonse [5 ]
机构：
[1] Univ Severino Sombra, Dept Biol, Vassouras, RJ, Brazil
[2] Fiocruz MS, Fundacao Oswaldo Cruz, Inst Oswaldo Cruz, Lab Diptera, BR-21045900 Rio De Janeiro, RJ, Brazil
[3] Fiocruz MS, Fundacao Oswaldo Cruz, Inst Oswaldo Cruz, Dept Biochem & Mol Biol, BR-21045900 Rio De Janeiro, RJ, Brazil
[4] Univ Fed Fluminense, Dept Organ Chem, BR-24001970 Niteroi, RJ, Brazil
[5] Univ Fed Fluminense, Dept Gen Biol, BR-24001970 Niteroi, RJ, Brazil
来源：
FITOTERAPIA | 2008年 / 79卷 / 01期
关键词：
Rhodnius prolixus; Neolignan; Burchellin; Biodegradation; Hemolymph;
D O I：
10.1016/j.fitote.2007.07.004
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The neolignan, burchellin, a natural compound that reduces urine excretion in larvae of the bloodsucking bug, Rhodnius prolixus, a vector of Chagas' disease, is rapidly degraded in the hemolymph of the insect. The main product that accumulates in this tissue has been shown to be piperonyl alcohol. Other catabolites have been identified by GC-MS analysis. (c) 2007 Published by Elsevier B.V.
引用
收藏
页码：59 / 63
页数：5
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