The Potential of Phage Therapy in Bacterial Infections of the Eye

被引：20

作者：

Gorski, Andrzej ^{[1
,3
]}

Targonska, Magdalena ^{[2
]}

Borysowski, Jan ^{[3
]}

Weber-Dabrowska, Beata ^{[1
]}

机构：

[1] Polish Acad Sci, L Hirszfeld Inst Immunol & Expt Therapy, PL-53114 Wroclaw, Poland

[2] Reg Specialist Hosp, Div Ophthalmol, Wroclaw, Poland

[3] Med Univ Warsaw, Warsaw, Poland

来源：

OPHTHALMOLOGICA | 2009年 / 223卷 / 03期

关键词：

Phage; Eye infections; Antibiotic resistance; Methicillin-resistant Staphylococcus aureus; RESISTANT STAPHYLOCOCCUS-AUREUS; PSEUDOMONAS-AERUGINOSA; BACTERIOPHAGE; MICE; ENDOPHTHALMITIS; BACTEREMIA; SPECTRUM;

D O I：

10.1159/000193293

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Antibiotic resistance has become a major health challenge which poses a significant threat, also in ophthalmology. For example, methicillin-resistant Staphylococcus aureus may cause dramatic complications, including bilateral blindness as a consequence of orbital cellulitis and panophthalmitis. This menace has provoked a greatly revived interest in phage therapy. In recent years, a number of papers have been published suggesting its efficacy in animal and human bacterial infections, but none of them addressed the phage potential in ophthalmology, which is the subject of this mini review. Copyright (C) 2009 S. Karger AG, Basel

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页码：162 / 165

页数：4

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