SYNTHESIS OF 2,4-DISUBSTITUTED THIAZOLES WITH 1,2,4-TRIAZOLE RING SYSTEM AS ANTIMICROBIAL AGENTS

被引:0
|
作者
Yadav, Ameya G. [1 ]
Bobade, A. S. [1 ]
Athlekar, S. V. [1 ]
Chowdhary, A. S. [1 ]
Patil, V. N. [1 ]
机构
[1] Haffkine Inst Training Res & Testing, Dept Chemotherapy, Bombay 400012, Maharashtra, India
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中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A facile synthesis of novel 2-{4'-[1-(1,2,4-triazolyl) methyl] phenyl}-4-(substituted) thiazoles (3a-j) has been carried out by condensation of 4'-[1-(1,2,4-triazolyl) methyl] benzothioamide (2) with various substituted aryl/heteroaryl alpha-haloketones. The synthesized compounds were screened for their possible antimicrobial activity.
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页码:21 / 24
页数:4
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