Xylomexicanins A and B, New Δ14,15-Mexicanolides from Seeds of the Chinese Mangrove Xylocarpus granatum

被引:0
|
作者
Shen, Li-Ru [1 ]
Dong, Mei [2 ]
Guo, Dong [3 ]
Yin, Bao-Wei [1 ]
Zhang, Man-Li [1 ]
Sha, Qing-Wen [1 ]
Huo, Chang-Hong [1 ]
Kiyota, Hiromasa [4 ]
Suzuki, Nobuo [5 ]
Cong, Bin [2 ]
机构
[1] Hebei Med Univ, Dept Med Nat Prod Chem, Sch Pharmaceut Sci, Shijiazhuang 050017, Hebei Prov, Peoples R China
[2] Hebei Med Univ, Coll Basic Med, Shijiazhuang 050017, Peoples R China
[3] New Drug R&D Co Ltd, N China Pharmaceut Grp Corp, Shijiazhuang 050035, Hebei Prov, Peoples R China
[4] Tohoku Univ, Dept Biosci & Biotechnol Future Bioind, Grad Sch Agr Sci, Aoba Ku, Sendai, Miyagi 9818555, Japan
[5] Chiba Univ, Dept Environm Biochem, Grad Sch Med, Chuo Ku, Chiba 2608670, Japan
基金
中国博士后科学基金; 日本学术振兴会;
关键词
Xylocarpus granatum; Limonoids; Antiproliferative Activity; XYLOGRANATINS A-D; LIMONOIDS; MEXICANOLIDES; FRUIT; RSA;
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Two new mexicanolide-type limonoids, named xylomexicanin A (1) and xylomexicanin B (2), were isolated from seeds of the Chinese mangrove Xylocarpus granatum. Their structures were elucidated on the basis of spectroscopic methods. Compound 1 exhibited antiproliferative activity against human breast carcinoma cells (KT), while 2 did not show inhibitory effects on eleven human tumour cell lines tested.
引用
收藏
页码:37 / 42
页数:6
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