THE TRANSCRIPTION FACTORS IKZF1 AND IKZF3 CONTROL B CELL ACTIVATION AND DIFFERENTIATION IN SYSTEMIC LUPUS ERYTHEMATOSUS

被引：1
|
作者：
Manou-Stathopoulou, Sotiria [1 ]
Rivellese, Felice [1 ]
Mauro, Daniele [1 ]
Goldmann, Katriona [1 ]
Pyne, Debasish [2 ]
Schafer, Peter [3 ]
Bombardieri, Michele [1 ]
Pitzalis, Costantino [1 ]
Lewis, Myles [1 ]
机构：
[1] Queen Mary Univ London, William Harvey Res Inst, Expt Med & Rheumatol, London, England
[2] Barts Hlth NHS Trust, Rheumatol, London, England
[3] Celgene Corp, Summit, NJ USA
来源：
ANNALS OF THE RHEUMATIC DISEASES | 2019年 / 78卷
关键词：
D O I：
10.1136/annrheumdis-2019-eular.6343
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
AB0179
引用
收藏
页码：1548 / 1548
页数：1
相关论文
共 50 条
  • [21] Effects of targeting the transcription factors Ikaros and Aiolos on B cell activation and differentiation in systemic lupus erythematosus
    Rivellese, Felice
    Manou-Stathopoulou, Sotiria
    Mauro, Daniele
    Goldmann, Katriona
    Pyne, Debasish
    Rajakariar, Ravindra
    Gordon, Patrick
    Schafer, Peter
    Bombardieri, Michele
    Pitzalis, Costantino
    Lewis, Myles J.
    LUPUS SCIENCE & MEDICINE, 2021, 8 (01):
  • [22] The recombinome of IKZF1 deletions in B-cell precursor ALL
    Bruno A. Lopes
    Claus Meyer
    Heloysa Bouzada
    Marius Külp
    Ana Luiza Tardem Maciel
    Patrizia Larghero
    Thayana C. Barbosa
    Caroline P. Poubel
    Caroline Barbieri
    Nicola C. Venn
    Luciano Dalla Pozza
    Draga Barbaric
    Chiara Palmi
    Grazia Fazio
    Claudia Saitta
    Thais F. Aguiar
    Mecneide M. Lins
    Maura R. V. Ikoma-Colturato
    Marcia Schramm
    Eduardo Chapchap
    Gianni Cazzaniga
    Rosemary Sutton
    Rolf Marschalek
    Mariana Emerenciano
    Leukemia, 2023, 37 : 1727 - 1731
  • [23] IKZF1plusplus? Investigating the genetic complexity of IKZF1 deleted B-cell acute lymphoblastic leukemia
    Luehmann, J. L.
    Hofmann, W.
    Bergmann, A. K.
    Moericke, A.
    Cario, G.
    Schrappe, M.
    Schlegelberger, B.
    Zimmermann, M.
    Stanulla, M.
    Steinemann, D.
    KLINISCHE PADIATRIE, 2023, 235 (03): : 198 - 198
  • [24] Down-regulated expression of IKZF1 mRNA in peripheral blood mononuclear cells from patients with systemic lupus erythematosus
    Wenlong Hu
    Liangdan Sun
    Jinping Gao
    Yun Li
    Peiguang Wang
    Yilin Cheng
    Tingmeng Pan
    Jianwen Han
    Yangsheng Liu
    Wensheng Lu
    Xianbo Zuo
    Yujun Sheng
    Sha Yao
    Caifeng He
    Zeying Yu
    Xianyong Yin
    Yong Cui
    Sen Yang
    Xuejun Zhang
    Rheumatology International, 2011, 31 : 819 - 822
  • [25] The recombinome of IKZF1 deletions in B-cell precursor ALL
    Lopes, Bruno A. A.
    Meyer, Claus
    Bouzada, Heloysa
    Kulp, Marius
    Maciel, Ana Luiza Tardem
    Larghero, Patrizia
    Barbosa, Thayana C. C.
    Poubel, Caroline P. P.
    Barbieri, Caroline
    Venn, Nicola C. C.
    Pozza, Luciano Dalla
    Barbaric, Draga
    Palmi, Chiara
    Fazio, Grazia
    Saitta, Claudia
    Aguiar, Thais F. F.
    Lins, Mecneide M. M.
    Ikoma-Colturato, Maura R. V.
    Schramm, Marcia
    Chapchap, Eduardo
    Cazzaniga, Gianni
    Sutton, Rosemary
    Marschalek, Rolf
    Emerenciano, Mariana
    LEUKEMIA, 2023, 37 (08) : 1727 - 1731
  • [26] A New Cause of Mendelian Lupus Due to IKZF1 Mutation Underlines the B Cell Landscape Heterogeneity in Monogenic Lupus
    Belot, Alexandre
    Frachette, Cecile
    Ommar, Omarjee Sulliman
    Mathieu, Anne-Laure
    Andrieu, Thibault
    Mondier, Paul
    Rice, Gillian
    Reumaux, Heloise
    Launay, David
    Lambert, Marc
    Lefevre, Guillaume
    Fabien, Nicole
    Malcus, Christophe
    Rouvet, Isabelle
    Chopin, Emilie
    Michallet, Anne-Sophie
    Defrance, Thierry
    Walzer, Thierry
    Crow, Yanick J.
    ARTHRITIS & RHEUMATOLOGY, 2017, 69
  • [27] Down-regulated expression of IKZF1 mRNA in peripheral blood mononuclear cells from patients with systemic lupus erythematosus
    Hu, Wenlong
    Sun, Liangdan
    Gao, Jinping
    Li, Yun
    Wang, Peiguang
    Cheng, Yilin
    Pan, Tingmeng
    Han, Jianwen
    Liu, Yangsheng
    Lu, Wensheng
    Zuo, Xianbo
    Sheng, Yujun
    Yao, Sha
    He, Caifeng
    Yu, Zeying
    Yin, Xianyong
    Cui, Yong
    Yang, Sen
    Zhang, Xuejun
    RHEUMATOLOGY INTERNATIONAL, 2011, 31 (06) : 819 - 822
  • [28] Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with Systemic Lupus Erythematosus
    Graham, Deborah S. Cunninghame
    Morris, David L.
    Bhangale, Tushar R.
    Criswell, Lindsey A.
    Syvanen, Ann-Christine
    Ronnblom, Lars
    Behrens, Timothy W.
    Graham, Robert R.
    Vyse, Timothy J.
    PLOS GENETICS, 2011, 7 (10):
  • [29] Gene-gene interactions of IRF5, STAT4, IKZF1 and ETS1 in systemic lupus erythematosus
    Dang, J.
    Shan, S.
    Li, J.
    Zhao, H.
    Xin, Q.
    Liu, Y.
    Bian, X.
    Liu, Q.
    TISSUE ANTIGENS, 2014, 83 (06): : 401 - 408
  • [30] Inhibition of CDK4/CDK6 Sensitizes Myeloma to IMiD By Reducing the MEIS2 to Cereblon Ratio That Accelerates IKZF1 and IKZF3 Degradation
    Huang, Xiangao
    Jayabalan, David
    Di Liberto, Maurizio
    Chen, Zhengming
    Schinzel, Anna C.
    Ely, Scott
    Rossi, Adriana C.
    Pearse, Roger N.
    Aneja, Ekta
    Coleman, Morton
    Lane, Joseph M.
    Hahn, William C.
    Mark, Tomer M.
    Niesvizky, Ruben
    Chen-Kiang, Selina
    BLOOD, 2015, 126 (23)
12345