Potential strategies to reduce medial compartment loading in patients with knee osteoarthritis of varying severity -: Reduced walking speed
被引:325
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作者:
Mündermann, A
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机构:Stanford Univ, Stanford, CA 94305 USA
Mündermann, A
Dyrby, CO
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机构:Stanford Univ, Stanford, CA 94305 USA
Dyrby, CO
Hurwitz, DE
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机构:Stanford Univ, Stanford, CA 94305 USA
Hurwitz, DE
Sharma, L
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机构:Stanford Univ, Stanford, CA 94305 USA
Sharma, L
Andriacchi, TP
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机构:Stanford Univ, Stanford, CA 94305 USA
Andriacchi, TP
机构:
[1] Stanford Univ, Stanford, CA 94305 USA
[2] Rush Presbyterian St Lukes Med Ctr, Chicago, IL 60612 USA
[3] Northwestern Univ, Feinberg Sch Med, Chicago, IL 60611 USA
[4] Stanford Univ, Ctr Med, Stanford, CA 94305 USA
[5] Palo Alto Vet Adm, Ctr Bone & Joint, Palo Alto, CA USA
来源:
ARTHRITIS AND RHEUMATISM
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2004年
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50卷
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04期
关键词:
D O I:
10.1002/art.20132
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Objective. To determine whether reducing walking speed is a strategy used by patients with knee osteoarthritis (OA) of varying disease severity to reduce the maximum knee adduction moment. Methods. Self-selected walking speeds and maximum knee adduction moments of 44 patients with medial tibiofemoral OA of varying disease severity, as assessed by using the Kellgren/Lawrence grade, were compared with those of 44 asymptomatic control subjects matched for sex, age, height, and weight. Results. Differences in self-selected normal walking speed explained only 8.9% of the variation in maximum knee adduction moment for the group of patients with knee OA. The severity of the disease influenced the adduction moment-walking speed relationship; the individual slopes of this relationship were significantly greater in patients with less severe OA than in asymptomatic matched control subjects. Self-selected walking speed did not differ between patients with knee OA, regardless of the severity, and asymptomatic control subjects. However, knees with more-severe OA had significantly greater adduction moments (mean +/- SD 3.80 +/- 0.89% body weight x height) and were in more varus alignment (6.0 +/- 4.5degrees) than knees with less-severe OA (2.94 +/- 0.70% body weight x height; and 0.0 +/- 2.9degrees, respectively). Conclusion. Patients with less-severe OA adapt a walking style that differs from that of patients with more-severe OA and controls. This walking style is associated with the potential to reduce the adduction moment when walking at slower speeds and could be linked to decreased disease severity.
机构:
Univ Pittsburgh, Dept Orthopaed Surg, Biodynam Lab, 3820 South Water St, Pittsburgh, PA 15203 USA
Kobe Univ, Grad Sch Med, Dept Orthopaed Surg, Kobe, Hyogo, JapanUniv Pittsburgh, Dept Orthopaed Surg, Biodynam Lab, 3820 South Water St, Pittsburgh, PA 15203 USA
Nagai, Kanto
Yang, Shumeng
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机构:
Univ Pittsburgh, Dept Orthopaed Surg, Biodynam Lab, 3820 South Water St, Pittsburgh, PA 15203 USAUniv Pittsburgh, Dept Orthopaed Surg, Biodynam Lab, 3820 South Water St, Pittsburgh, PA 15203 USA
Yang, Shumeng
Fu, Freddie H.
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机构:
Univ Pittsburgh, Dept Orthopaed Surg, Biodynam Lab, 3820 South Water St, Pittsburgh, PA 15203 USAUniv Pittsburgh, Dept Orthopaed Surg, Biodynam Lab, 3820 South Water St, Pittsburgh, PA 15203 USA
Fu, Freddie H.
Anderst, William
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机构:
Univ Pittsburgh, Dept Orthopaed Surg, Biodynam Lab, 3820 South Water St, Pittsburgh, PA 15203 USAUniv Pittsburgh, Dept Orthopaed Surg, Biodynam Lab, 3820 South Water St, Pittsburgh, PA 15203 USA
机构:
VA Palo Alto Hlth Care Syst, Palo Alto, CA 94304 USA
Stanford Univ, Dept Mech Engn, 452 Escondido Mall,Bldg 520,Room 243, Stanford, CA 94305 USAVA Palo Alto Hlth Care Syst, Palo Alto, CA 94304 USA
Asay, Jessica L.
Erhart-Hledik, Jennifer C.
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机构:
Stanford Univ, Dept Mech Engn, 452 Escondido Mall,Bldg 520,Room 243, Stanford, CA 94305 USA
Stanford Univ, Med Ctr, Dept Orthoped Surg, Stanford, CA 94305 USAVA Palo Alto Hlth Care Syst, Palo Alto, CA 94304 USA
Erhart-Hledik, Jennifer C.
Andriacchi, Thomas P.
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h-index: 0
机构:
VA Palo Alto Hlth Care Syst, Palo Alto, CA 94304 USA
Stanford Univ, Dept Mech Engn, 452 Escondido Mall,Bldg 520,Room 243, Stanford, CA 94305 USA
Stanford Univ, Med Ctr, Dept Orthoped Surg, Stanford, CA 94305 USAVA Palo Alto Hlth Care Syst, Palo Alto, CA 94304 USA