Inhibition of both cyclooxygenase (COX)-1 and COX-2 is required for NSAID-induced erosion formation.

被引：6
|
作者：
Wallace, JL [1 ]
McKnight, WK [1 ]
Vergnolle, N [1 ]
机构：
[1] Univ Calgary, Calgary, AB, Canada
来源：
GASTROENTEROLOGY | 2000年 / 118卷 / 04期
关键词：
D O I：
10.1016/S0016-5085(00)82848-6
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
1227
引用
收藏
页码：A194 / A194
页数：1
相关论文
共 50 条
  • [21] Expression of cyclooxygenase (COX)-1 and COX-2 in adaptive cytoprotection induced by mild stress
    Brzozowski, T
    Konturek, PC
    Konturek, SJ
    Drozdowicz, D
    Pajdo, R
    Pawlik, M
    Brzozowska, I
    Hahn, EG
    JOURNAL OF PHYSIOLOGY-PARIS, 2000, 94 (02) : 83 - 91
  • [22] Cancer and cyclooxygenase-2 (COX-2) inhibition
    Evans, JF
    Kargman, SL
    CURRENT PHARMACEUTICAL DESIGN, 2004, 10 (06) : 627 - 634
  • [23] Differential effects of inhibition of isoforms of cyclooxygenase (COX-1, COX-2) in chronic inflammation
    D. W. Gilroy
    A. Tomlinson
    D. A. Willoughby
    Inflammation Research, 1998, 47 : 79 - 85
  • [24] Differential effects of inhibition of isoforms of cyclooxygenase (COX-1, COX-2) in chronic inflammation
    Gilroy, DW
    Tomlinson, A
    Willoughby, DA
    INFLAMMATION RESEARCH, 1998, 47 (02) : 79 - 85
  • [25] Cyclooxygenase (COX)-1 and COX-2 Both Play an Important Role in the Protection of the Duodenal Mucosa in Cats
    Satoh, Hiroshi
    Amagase, Kikuko
    Ebara, Satomi
    Akiba, Yasutada
    Takeuchi, Koji
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2013, 344 (01): : 189 - 195
  • [26] BOTH ISOFORMS OF CYCLOOXYGENASE (COX-1 AND COX-2) CAN BE EXPRESSED BY CULTURED HUMAN KERATINOCYTES
    GOLDYNE, ME
    EVANS, CB
    HABIB, A
    MACLOUF, J
    CLINICAL RESEARCH, 1994, 42 (01): : A41 - A41
  • [27] The MEK/ERK pathway mediates COX-2-selective NSAID-induced apoptosis and induced COX-2 protein expression in colorectal carcinoma cells
    Elder, DJE
    Halton, DE
    Playle, LC
    Paraskeva, C
    INTERNATIONAL JOURNAL OF CANCER, 2002, 99 (03) : 323 - 327
  • [28] Recent advances in inducible cyclooxygenase (COX-2) inhibition
    de Leval, X
    Delarge, J
    Somers, F
    de Tullio, P
    Henrotin, Y
    Pirotte, B
    Dogné, JM
    CURRENT MEDICINAL CHEMISTRY, 2000, 7 (10) : 1041 - 1062
  • [29] COX inhibition and NSAID-induced gastric damage - Roles in various pathogenic events
    Takeuchi, K
    Tanaka, A
    Hayashi, Y
    Yokota, A
    CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2005, 5 (05) : 475 - 486
  • [30] High cyclooxygenase 1 (COX-1) and cyclooxygenase 2 (COX-2) contents in mouse lung tumors
    Bauer, AK
    Dwyer-Nield, LD
    Malkinson, AM
    CARCINOGENESIS, 2000, 21 (04) : 543 - 550
12345