Reaction of 2-oxoindolin-3-ylidene derivatives with heterocyclic enamines, a convenient one-pot synthesis of pyrimido [5,4:5′,6′]pyrido[2,3-b]indole-2, 4-dione and spiro indolin-2-one-3, 5′-pyrido [2,3-d] pyrimidines

被引：6

作者：

El-Ahl, AAS ^{[1
]}

机构：

[1] Mansoura Univ, Dept Chem, Fac Sci, Mansoura, Egypt

来源：

SYNTHETIC COMMUNICATIONS | 2000年 / 30卷 / 12期

关键词：

D O I：

10.1080/00397910008087401

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of 6-aminouracils 2a, b with 2-oxoindolin-3-ylideneacetophenones la-h afforded Pyrimido[5,4:5', 6'] pyrido-[2, 3-b] indole- 2, 4-diones 3 a-k via a regiospecific Michael addition, followed by cyclization, Alternatively, the reaction of 2a with 2-oxoindolin-3-ylidenemalononitriles 6a, b gave rise to regiospecific formation of spiro indolin-2-one-3, 5'-pyrido[2,3-d]pyrimidines 7a,b.

引用

页码：2223 / 2231

页数：9

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