Investigation of necessary conditions for imaging cell analysis using EIT

被引：0

作者：

Gibas, Christian ^{[1
]}

Veckollari, Birgyl ^{[2
,3
]}

Schulte, Gregor ^{[2
,3
]}

Mueller, Mareike ^{[2
,3
]}

Brueck, Rainer ^{[1
]}

Schoenherr, Holger ^{[2
,3
]}

机构：

[1] Univ Siegen, Med Informat & Microsyst Design, Holderlinstr 3, D-57076 Siegen, Germany

[2] Univ Siegen, Phys Chem 1, Adolf Reichwein Str 2, D-57076 Siegen, Germany

[3] Univ Siegen, Res Ctr Micro & Nanochem & Engn C, Adolf Reichwein Str 2, D-57076 Siegen, Germany

来源：

MEDICAL IMAGING 2019: BIOMEDICAL APPLICATIONS IN MOLECULAR, STRUCTURAL, AND FUNCTIONAL IMAGING | 2019年 / 10953卷

关键词：

Cellular Imaging; EIT imaging; EIT chip; Differential Image Reconstruction; TISSUE;

D O I：

10.1117/12.2512404

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Electrical Impedance Tomography (EIT) is a method used to record the impedance distribution within a target. The best-known application of EIT is lung diagnostics using imaging algorithms. However, apart from this, there are individual research projects dealing with imaging analysis at the cellular level. For example, cell analysis using EIT can help to distinguish diseased cells from healthy cells. To achieve this goal, an existing EIT system was combined with a new EIT chip in a first step. This chip allows analysis in very small dimensions. Various parameters such as the diameter of the measuring environment, the necessary conductive solutions or the measuring methods used were varied and evaluated. In a next step, various image reconstructions were carried out using data acquired with C. elegans.

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页数：12

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