Conjugate addition of thiols and malonates to thiocinnamates under PTC conditions

被引：6

作者：

Marzorati, L ^{[1
]}

de Mattos, MC ^{[1
]}

Wladislaw, B ^{[1
]}

Di Vitta, C ^{[1
]}

机构：

[1] Univ Sao Paulo, Inst Quim, BR-05513970 Sao Paulo, Brazil

来源：

SYNTHETIC COMMUNICATIONS | 2002年 / 32卷 / 09期

基金：

巴西圣保罗研究基金会;

关键词：

thiocinnamates; conjugate addition; phase transfer catalysis; pyrrolidinone;

D O I：

10.1081/SCC-120003641

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Addition of thiols or diethylmalonate to thiocinnamate, under solid-liquid PTC conditions, afforded the corresponding 1,4-adducts in moderate to good yields. A 2-pyrrolidinone was obtained using diethyl N-acetamidomalonate as Michael donor, via intramolecular cyclization of the parent adduct.

引用

页码：1427 / 1435

页数：9

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