An efficient base-mediated intramolecular condensation of 2-(disubstituted amino)-benzonitriles to 3-aminoindoles

被引：17
|
作者：
Seong, Churl Min [1 ]
Park, Chul Min [1 ]
Choi, Jinil [1 ]
Park, No Sang [1 ]
机构：
[1] Korea Res Inst Chem Technol, Ctr Med Chem, Drug Discovery Div, Taejon 305606, South Korea
来源：
TETRAHEDRON LETTERS | 2009年 / 50卷 / 09期
关键词：
3-Aminoindoles; Disubstituted amino-benzonitriles; Base-mediated cyclization; In situ acetylation; INDOLES;
D O I：
10.1016/j.tetlet.2008.12.052
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A concise and versatile method for the preparation of 3-aminoindoles from 2-(disubstituted amino)-benzonitriles is described, and in situ functionalizations were illustrated. (C) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1029 / 1031
页数：3
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