Remeron (mirtazapine): A novel antidepressant that disinhibits serotonin and norepinephrine by alpha 2 antagonism

被引：0
|
作者：
Stahl, SM
机构：
[1] UNIV CALIF SAN DIEGO,SCH MED,CLIN NEUROSCI RES CTR,LA JOLLA,CA 92093
[2] UNIV CALIF SAN DIEGO,SCH MED,DEPT PSYCHIAT,LA JOLLA,CA 92093
来源：
PSYCHIATRIC ANNALS | 1997年 / 27卷 / 01期
关键词：
D O I：
暂无
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
引用
收藏
页码：14 / 16
页数：3
相关论文
共 50 条
  • [21] INTERACTION OF NEUROLEPTICS AND ANTIDEPRESSANTS WITH RAT-BRAIN ALPHA-2-RECEPTORS - A POSSIBLE RELATIONSHIP BETWEEN ALPHA-2-RECEPTOR ANTAGONISM AND ANTIDEPRESSANT ACTION
    TSUKAMOTO, T
    ASAKURA, M
    HIRATA, N
    IMAFUKU, J
    MATSUI, H
    HASEGAWA, K
    BIOLOGICAL PSYCHIATRY, 1984, 19 (09) : 1283 - 1291
  • [22] MEASUREMENT OF HAMSTER CORE TEMPERATURE BY TELEMETRY - EFFECTS OF NOREPINEPHRINE, SEROTONIN AND PROSTAGLANDINS-E2 AND F2 ALPHA
    MILLER, WL
    SUTTON, MJ
    FEDERATION PROCEEDINGS, 1974, 33 (03) : 589 - 589
  • [23] ANTAGONISM OF ALPHA2A-ADRENOCEPTOR: A NOVEL APPROACH TO INHIBIT INFLAMMATORY RESPONSES IN SEPSIS
    Zhang, F.
    Wu, R.
    Qiang, X.
    Zhou, M.
    Wang, P.
    SHOCK, 2009, 31 : 80 - 80
  • [24] Risperidone dose-dependently increases serotonin release in the rat frontal cortex: Role of alpha 2 adrenoceptor antagonism
    Hertel, P
    Nomikos, GG
    Svensson, TH
    NORDIC JOURNAL OF PSYCHIATRY, 1996, 50 (02) : 91 - 91
  • [25] Tricyclic isoxazolines:: Identification of R226161 as a potential new antidepressant that combines potent serotonin reuptake inhibition and α2-adrenoceptor antagonism
    Andres, J. Ignacio
    Alcazar, Jesus
    Alonso, Jose M.
    Alvarez, Rosa M.
    Bakker, Margot H.
    Biesmans, Ilse
    Cid, Jose M.
    De Lucas, Ana I.
    Drinkenburg, Wilhelmus
    Fernandez, Javier
    Font, Luis M.
    Iturrino, Laura
    Langlois, Xavier
    Lenaerts, Ilse
    Martinez, Sonia
    Megens, Anton A.
    Pastor, Joaquin
    Pullan, Shirley
    Steckler, Thomas
    BIOORGANIC & MEDICINAL CHEMISTRY, 2007, 15 (11) : 3649 - 3660
  • [26] Pharmacological depletion of serotonin and norepinephrine with para-chlorophenylalanine and alpha-methyl-p-tyrosine reverses the antidepressant-like effects of adolescent caffeine exposure in the male rat
    Turgeon, Sarah M.
    Abdulzahir, Alifayaz
    Hwang, Kaylin
    Sanford, Jordan
    BEHAVIOURAL PHARMACOLOGY, 2020, 31 (08): : 768 - 775
  • [27] The novel melatonergic antidepressant, agomelatine, is a neutral antagonist at constitutively-active serotonin2C receptors
    Millan, M.
    Marin, P.
    Kamal, M.
    Jockers, R.
    Chanrion, B.
    Labasque, M.
    Bockaert, J.
    la Cour, C. Mannoury
    INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2010, 13 : 79 - 79
  • [28] The novel antidepressant, S35966, is a mixed serotonin and noradrenaline reuptake inhibitor and an antagonist at α2-adrenoceptors
    Gobert, A
    Cussac, D
    Lejeune, F
    Newman-Tancredi, A
    Audinot, V
    Boutin, JA
    Carr, C
    Milligan, G
    Rivet, JM
    Brocco, M
    Dekeyne, A
    Lacoste, JM
    Cordi, A
    Millan, MJ
    EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2002, 12 : S248 - S248
  • [29] Differentiated effects of the multimodal antidepressant vortioxetine on sleep architecture: Part 2, pharmacological interactions in rodents suggest a role of serotonin-3 receptor antagonism
    Leiser, Steven C.
    Iglesias-Bregna, Deborah
    Westrich, Ligia
    Pehrson, Alan L.
    Sanchez, Connie
    JOURNAL OF PSYCHOPHARMACOLOGY, 2015, 29 (10) : 1092 - 1105
  • [30] Risperidone dose-dependently increases extracellular concentrations of serotonin in the rat frontal cortex: Role of alpha(2)-adrenoceptor antagonism
    Hertel, P
    Nomikos, GG
    Schilstrom, B
    Arborelius, L
    Svensson, TH
    NEUROPSYCHOPHARMACOLOGY, 1997, 17 (01) : 44 - 55
12345