Synthesis and biological activity of certain 1-substituted-4-benzylidene-2-phenyl-5-imidazolones

被引：0
|
作者：
Arief, MMH [1 ]
机构：
[1] Benha Univ, Fac Sci, Dept Chem, Benha, Egypt
来源：
REVUE ROUMAINE DE CHIMIE | 1999年 / 44卷 / 02期
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D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A novel series of 1-substituted-4-benzylidene-2-phenyl-5-imidazolone derivatives were synthesized for their potential biological activity. The synthesis involved the base and acid catalyzed reactions of azide 3 and/or acid chloride 2. Compounds 5c and 5d were easily cyclized to give 1,3,4-oxadiazole derivatives 6a and 6b. Representative examples for internal Friedel-Crafts and [4 + 2] cycloaddition were also investigated.
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页码：173 / 179
页数：7
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