New Method for the Synthesis and Reactivity of (5-R-1,3,4-Oxadiazol-2-yl)furoxans

被引：18
|
作者：
Fershtat, Leonid L. [1 ]
Kulikov, Alexander S. [1 ]
Ananyev, Ivan V. [2 ]
Struchkova, Marina I. [1 ]
Makhova, Nina N. [1 ]
机构：
[1] Russian Acad Sci, ND Zelinsky Inst Organ Chem, 47 Leninsky Pr, Moscow 119991, Russia
[2] Russian Acad Sci, AN Nesmeyanov Inst Organoelement Cpds, 28 Vavilova St, Moscow 119991, Russia
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 2016年 / 53卷 / 01期
关键词：
DERIVATIVES; ACID;
D O I：
10.1002/jhet.1940
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new, simple and general one-pot method for the preparation of (5-R-1,3,4-oxadiazol-2-yl)furoxans has been developed on the basis of the interaction between accessible 3-methylfuroxan-4-carboxylic acid hydrazide and aliphatic, aromatic and heterocyclic carboxylic acids or their chlorides in the presence of POCl3. The synthesis and study of (5-R-1,3,4-oxadiazol-2-yl)furoxans reactivity resulted in new polyheterocyclic ensembles incorporating furoxan, 1,3,4-oxadiazole, pyrrole, triazole, furan, thiophene, pyrimidine, and other heterocycles in different combinations.
引用
收藏
页码：102 / 108
页数：7
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