A Compact NIR Fluorescence Imaging System with Goggle Display for Intraoperative Guidance

被引:0
|
作者
Gao, Shengkui [1 ]
Mondal, Suman [2 ]
Zhu, Nan [3 ]
Liang, Rongguang [3 ]
Achilefu, Samuel [2 ]
Gruev, Viktor [1 ]
机构
[1] Washington Univ, Dept Comp Sci & Engn, St Louis, MO USA
[2] Washington Univ, Dept Radiol, St Louis, MO USA
[3] Univ Arizona, Coll Opt Sci, Tucson, AZ USA
关键词
NIR fluorescence imaging; sensor system; CMOS imaging sensor; wearable device; image guided surgery;
D O I
暂无
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
Near infra-red (NIR) fluorescence imaging offers high sensitivity and specificity for cancer detection and tumor margin localization. In this paper, a compact and wearable NIR fluorescence imaging system (FIS) for image guided surgery is presented. The proposed FIS captures 27 frames per second of both NIR and visible spectrum data, allowing for minimum detection of 10nM of ICG concentration. The design tradeoffs of the complete system are carefully analyzed. The performance of the proposed FIS is evaluated under both sensitivity test and experimental mouse study. The imaging system is currently used in clinical trials for imaging sentinel lymph nodes in breast cancer and melanoma patients.
引用
收藏
页码:1622 / 1625
页数:4
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