Alarming rates of virological failure and drug resistance in patients on long-term antiretroviral treatment in routine HIV clinics in Togo

被引：14

作者：

Konou, Abla A. ^{[1
]}

Dagnra, Anoumou Y. ^{[1
,2
]}

Vidal, Nicole ^{[3
]}

Salou, Mounerou ^{[1
,2
]}

Adam, Zakillatou ^{[4
]}

Singo-tokofai, Assetina ^{[4
]}

Delaporte, Eric ^{[3
]}

Prince-david, Mireille ^{[1
,2
]}

Peeters, Martine ^{[3
]}

机构：

[1] Univ Lome, Fac Sci Sante, Lab Biol Mol & Immunol BIOLIM FSS UL, Lome, Togo

[2] Univ Lome, Fac Sci Sante, Dept Sci Fondamentales & Biol, Lome, Togo

[3] Univ Montpellier, INSERM, U1175, IRD,UMI 233, F-34059 Montpellier, France

[4] PNLS, Lome, Togo

来源：

AIDS | 2015年 / 29卷 / 18期

关键词：

SUB-SAHARAN AFRICA; THERAPY;

D O I：

10.1097/QAD.0000000000000906

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Information on efficacy of long-term antiretroviral treatment (ART) exposure in resource-limited countries is still scarce. In 767 patients attending routine HIV centers in Togo and receiving first-line ART for more than four years, 42% had viral load greater than 1000copies/ml and either were on a completely ineffective ART regime or were with only a single drug active. The actual conditions to ensure lifelong ART in resource-limited countries can have dramatic long-term outcomes.

引用

页码：2527 / 2530

页数：4

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