Robust correlation of Galectin-9 expression with immunological tumor features and outcome in multiple tumor types establishes it as both a novel therapeutic target and a biomarker

被引:0
|
作者
Filipovic, Aleksandra [1 ]
Koide, Shohei [2 ]
Chen, Linxiao [2 ]
Ting, David T. [3 ]
Ilyas, Mohammad [4 ]
Fadhil, Wakkas [4 ]
Rakha, Emad [4 ,5 ]
Green, Andrew [4 ,5 ]
机构
[1] PureTech Hlth, Boston, MA USA
[2] NYU, Perlmutter Canc Ctr, New York, NY USA
[3] Massachusetts Gen Hosp, Canc Ctr, Boston, MA 02114 USA
[4] Univ Nottingham, Sch Med, Div Canc & Stem Cells, Biodiscovery Inst, Nottingham, England
[5] Nottingham City Hosp, Dept Histopathol, Nottingham, England
关键词
D O I
10.1158/1538-7445.AM2020-LB-350
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
LB-350
引用
收藏
页数:2
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    Liu, Yuan
    Robinson, Brian
    Krasinskas, Alyssa
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    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2024, 42 (3_SUPPL) : 555 - 555
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    Azad, Nilofer S.
    Yarchoan, Mark
    Maithel, Shishir K.
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    Lesinski, Gregory B.
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    Gan, Xinxin
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