Galectin-9 is a regulator of immune interactions in the tumor microenvironment and represents a novel therapeutic target in biliary tract cancer

被引:0
|
作者
Warren, Emilie A. K. [1 ]
Hammons, Jacklyn N. [2 ]
Keilson, Jessica M. [1 ]
Rivera, Guillermo O. Rangel [3 ]
Wyatt, Megan M. [3 ]
Goel, Caroline R. [1 ]
Henry, Curtis J. [4 ]
Kulkarni, Sarah [5 ]
Li, Yuan [5 ]
Robinson, Brian [4 ]
Krasinskas, Alyssa M. [4 ]
Azad, Nilofer S. [6 ]
Yarchoan, Mark [7 ]
Maithel, Shishir K. [8 ]
Paulos, Chrystal M. [3 ]
Lesinski, Gregory B. [2 ]
机构
[1] Emory Univ, Atlanta, GA USA
[2] Emory Univ, Dept Hematol & Med Oncol, Winship Canc Inst, Atlanta, GA USA
[3] Emory Univ, Div Surg Oncol, Dept Surg, Dept Microbiol & Immunol,Winship Canc Inst, Atlanta, GA USA
[4] Emory Univ, Sch Med, Atlanta, GA USA
[5] Emory Univ, Rollins Sch Publ Hlth, Atlanta, GA USA
[6] Johns Hopkins Univ, Sch Med, Sidney Kimmel Comprehens Canc Ctr, Dept Med Oncol, Baltimore, MD USA
[7] Johns Hopkins Univ Hosp, Baltimore, MD USA
[8] Emory Univ, Winship Canc Inst, Atlanta, GA USA
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
54
引用
收藏
页码:S28 / S28
页数:1
相关论文
共 34 条
  • [1] Galectin-9 as a regulator of immune interactions in the tumor microenvironment and novel therapeutic target in biliary tract cancer.
    Warren, Emilie A. K.
    Hammons, Jacklyn
    Keilson, Jessica M.
    Wyatt, Megan
    Medin, Caroline
    Henry, Curtis
    Kulkarni, Sarah
    Liu, Yuan
    Robinson, Brian
    Krasinskas, Alyssa
    Maithel, Shishir K.
    Paulos, Chrystal M.
    Lesinski, Gregory B.
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2024, 42 (3_SUPPL) : 555 - 555
  • [2] Galectin-9 in cancer therapy: from immune checkpoint ligand to promising therapeutic target
    Zhang, Minpu
    Liu, Cun
    Li, Ye
    Li, Huayao
    Zhang, Wenfeng
    Liu, Jingyang
    Wang, Liquan
    Sun, Changgang
    [J]. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2024, 11
  • [3] Robust correlation of Galectin-9 expression with immunological tumor features and outcome in multiple tumor types establishes it as both a novel therapeutic target and a biomarker
    Filipovic, Aleksandra
    Koide, Shohei
    Chen, Linxiao
    Ting, David T.
    Ilyas, Mohammad
    Fadhil, Wakkas
    Rakha, Emad
    Green, Andrew
    [J]. CANCER RESEARCH, 2020, 80 (16)
  • [4] The Tim3-galectin-9 interactions in the tumor microenvironment of nasopharyngeal cancer.
    Kwong, Dora Lai Wan
    Kam, Ngar-Woon
    Tse, Wai Chun
    Lok, Sing Hei
    Tsao, George
    Lee, Victor Ho-Fun
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2021, 39 (15)
  • [5] The histone methyltransferase G9a: a new therapeutic target in biliary tract cancer
    Mayr, Christian
    Helm, Katharina
    Jakab, Martin
    Ritter, Markus
    Shrestha, Rajeev
    Makaju, Ramesh
    Wagner, Andrej
    Pichler, Martin
    Beyreis, Marlena
    Staettner, Stefan
    Jaeger, Tarkan
    Klieser, Eckhard
    Kiesslich, Tobias
    Neureiter, Daniel
    [J]. HUMAN PATHOLOGY, 2018, 72 : 117 - 126
  • [6] A Novel Prognostic Marker and Therapeutic Target Associated with Glioma Progression in a Tumor Immune Microenvironment
    Zhang, Jun-Jie
    Zhang, Yu
    Chen, Qian
    Chen, Qi-Ning
    Yang, Xin
    Zhu, Xiao-Lin
    Hao, Chun-Yan
    Duan, Hu-Bin
    [J]. JOURNAL OF INFLAMMATION RESEARCH, 2023, 16 : 895 - 916
  • [7] Spatial analysis of tumor-infiltrating lymphocytes in tumor microenvironment as biomarker for immune checkpoint inhibition in biliary tract cancer
    Bang, Yeong Hak
    Bang, Kyunghye
    Shin, Jin Ho
    Yoon, Hyunseok
    Kim, Kyu-Pyo
    Park, Inkeun
    Jeong, Jae Ho
    Chang, Heung-Moon
    Ryoo, Baek-Yeol
    Oum, Chiyoon
    Kim, Seulki
    Lim, Yoojoo
    Park, Gahee
    Ock, Chan-Young
    Yoo, Changhoon
    [J]. CANCER RESEARCH, 2023, 83 (07)
  • [8] The receptor tyrosine kinase Axl is an essential regulator of prostate cancer proliferation and tumor growth and represents a new therapeutic target
    J D Paccez
    G J Vasques
    R G Correa
    J F Vasconcellos
    K Duncan
    X Gu
    M Bhasin
    T A Libermann
    L F Zerbini
    [J]. Oncogene, 2013, 32 : 689 - 698
  • [9] ROR1 is upregulated in endometrial cancer and represents a novel therapeutic target (vol 9, 13906, 2020)
    Liu, Dongli
    Gunther, Kate
    Enriquez, Luis A.
    Daniels, Benjamin
    O'Mara, Tracy A.
    Tang, Katrina
    Spurdle, Amanda B.
    Ford, Caroline E.
    [J]. SCIENTIFIC REPORTS, 2022, 12 (01)
  • [10] MicroRNA-3613-3p functions as a tumor suppressor and represents a novel therapeutic target in breast cancer
    Chong Chen
    Yundi Pan
    Lipeng Bai
    Huilin Chen
    Zhaojun Duan
    Qin Si
    Ruizhe Zhu
    Tsung-Hsien Chuang
    Yunping Luo
    [J]. Breast Cancer Research, 23