Surfactant protein A and D of otitis media in the rat

被引：0
|
作者：
Kamimura, M [1 ]
Himi, T [1 ]
Mitsuzawa, H [1 ]
Konishi, M [1 ]
机构：
[1] Sapporo Med Univ, Sch Med, Dept Otolaryngol, Sapporo, Hokkaido, Japan
来源：
RECENT ADVANCES IN OTITIS MEDIA, PROCEEDINGS | 2001年
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Recently, the main role of Surfactant proteins A and D (SP-A and SP-D) are thought to be in the innate immunity at the level of the alveolus. We investigated whether SP-A and SP-D were expressed in the rat Eustachian tube and middle ear with otitis media. Immunostaining showed that SPA and SP-D were present in surface epithelial cells of the middle ear and Eustachian tube. The cell surface expression of SP-A and SP-D increased with otitis media compared to without otitis media. SP-A and SP-D may play an important role for the anti body-in dependent protection in the middle car and Eustachian tube.
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页码：203 / 207
页数：5
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