Review of recent research on biomedical applications of electrospun polymer nanofibers for improved wound healing

被引:129
|
作者
Hassiba, Alaa J. [1 ]
El Zowalaty, Mohamed E. [2 ]
Nasrallah, Gheyath K. [2 ,3 ]
Webster, Thomas J. [4 ,5 ,6 ]
Luyt, Adriaan S. [7 ]
Abdullah, Aboubakr M. [7 ]
Elzatahry, Ahmed A. [1 ]
机构
[1] Qatar Univ, Mat Sci & Technol Program, Coll Arts & Sci, Doha 2713, Qatar
[2] Qatar Univ, Biomed Res Ctr, Doha 2713, Qatar
[3] Qatar Univ, Dept Hlth Sci, Coll Arts & Sci, Doha 2713, Qatar
[4] Northeastern Univ, Dept Chem Engn, Boston, MA 02115 USA
[5] Northeastern Univ, Dept Bioengn, Boston, MA 02115 USA
[6] King Abdulaziz Univ, Ctr Excellence Adv Mat Res, Jeddah 21413, Saudi Arabia
[7] Qatar Univ, Ctr Adv Mat, Doha 2713, Qatar
关键词
activity; antimicrobial; biomedical; electrospinning; nanofibers; nanomaterials; wound dressings; SILK FIBROIN; CONTROLLED-RELEASE; DRUG-DELIVERY; COMPOSITE NANOFIBERS; ALCOHOL) NANOFIBERS; PROMISING MATERIALS; POLYVINYL-ALCOHOL; CROSS-LINKING; MATS; GELATIN;
D O I
10.2217/nnm.15.211
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Wound dressings play an important role in a patient's recovery from health problems, as unattended wounds could lead to serious complications such as infections or, ultimately, even death. Therefore, wound dressings since ancient times have been continuously developed, starting from simple dressings from natural materials for covering wounds to modern dressings with functionalized materials to aid in the wound healing process and enhance tissue repair. However, understanding the nature of a wound and the subsequent healing process is vital information upon which dressings can be tailored to ensure a patient's recovery. To date, much progress has been made through the use of nanomedicine in wound healing due to the ability of such materials to mimic the natural dimensions of tissue. This review provides an overview of recent studies on the physiology of wound healing and various wound dressing materials made of nanofibers fabricated using the electrospinning technique.
引用
收藏
页码:715 / 737
页数:23
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