Application of genetics and genomics in drug development

被引：0
|
作者：
Polymeropoulos, MH [1 ]
机构：
[1] Novartis Pharmaceut Corp, Pharmacogenet Dept, Gaithersburg, MD 20878 USA
来源：
DRUG DEVELOPMENT RESEARCH | 2000年 / 49卷 / 01期
关键词：
pharmacogenetics; Human Genome Project; DNA; polymorphism; EST; expressed sequence tag;
D O I：
10.1002/(SICI)1098-2299(200001)49:1<43::AID-DDR7>3.0.CO;2-V
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Pharmacogenetics is capitalizing on the tools of the Human Genome Project to introduce the new genomic information into drug development. The applications vary from identifying individuals at risk for a disease, to developing gene signatures of drug efficacy and adverse effects. Pharmacogenetics is a field in evolution from which significant growth is expected in the years to come. (C) 2000 Wiley-Liss, Inc.
引用
收藏
页码：43 / 45
页数：3
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