Orthopedic complications of solid-organ transplantation

被引:6
|
作者
Aaron, Roy K. [1 ]
Ciombor, Deborah McK. [1 ]
机构
[1] Brown Med Sch, Dept Orthopaed, Providence, RI 02906 USA
关键词
D O I
10.1016/j.suc.2006.06.014
中图分类号
R61 [外科手术学];
学科分类号
摘要
Organ transplantation has undeniably increased the longevity and quality of life of patients with end-stage organ failure. It has, however, introduced the skeletal complications of (1) fragility fractures and decreased bone density due to pretransplant bone loss and immunosuppressive therapy, and (2) avascular necrosis leading to subchondral fracture and secondary osteoarthritis. This article reviews these two skeletal complications of solid-organ transplantation that lead to structural failure of bone and result in significant morbidity and reduced quality of life.
引用
收藏
页码:1237 / +
页数:20
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