Cucurbiturils in nucleic acids research

被引：21

作者：

Chernikova, Ekaterina Y. ^{[1
]}

Berdnikova, Daria V. ^{[2
]}

机构：

[1] Russian Acad Sci, AN Nesmeyanov Inst Organoelement Cpds, Lab Photoact Supramol Syst, Vavilova St 28, Moscow, Russia

[2] Univ Siegen, Dept Chem Biol, Organ Chem 2, Adolf Reichwein Str 2, D-57076 Siegen, Germany

来源：

CHEMICAL COMMUNICATIONS | 2020年 / 56卷 / 98期

基金：

俄罗斯科学基金会;

关键词：

HOST-GUEST INTERACTIONS; DNA-BINDING; COMPLEXES; RNA; CHEMISTRY; PROTEIN; DISCRIMINATION; ARCHITECTURES; AGGREGATION; RESTRICTION;

D O I：

10.1039/d0cc06583h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

During the past ten years, the importance of cucurbiturils (CB[n]) as macrocyclic hosts in supramolecular assemblies with various types of natural and synthetic nucleic acids (NAs) has increased explosively. As a component of such systems, CB[n] macrocycles can play a wide spectrum of roles from drug and gene delivery vehicles to catalysts/inhibitors of biochemical reactions and even building blocks for NA-based materials. The aim of this highlight article is to describe the development of the CB[n] applications in nucleic acids research and to outline the current situation and perspectives of this fascinating synergistic combination of supramolecular chemistry of CB[n] and NAs.

引用

页码：15360 / 15376

页数：17

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