Biginelli reaction - an effective method for the synthesis of dihydropyrimidine derivatives (microreview)

被引：9

作者：

Simurova, Nathaliia ^{[1
]}

Maiboroda, Olena ^{[1
]}

机构：

[1] Natl Univ Food Technol, 68 Volodymyrska St, UA-01601 Kiev, Ukraine

来源：

CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2017年 / 53卷 / 04期

关键词：

SOLVENT-FREE CONDITIONS; MULTICOMPONENT REACTIONS; ONE-POT; 3-COMPONENT SYNTHESIS; IONIC LIQUID; EFFICIENT; CATALYST; 3,4-DIHYDROPYRIMIDINONES; CHEMISTRY; THIONES;

D O I：

10.1007/s10593-017-2067-z

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A brief review of the publications over the past 5 years devoted to the synthesis of 3,4-dihydropyrimidin-2(1H)-one or -thione derivatives using Biginelli reaction is presented. The impact of reaction conditions (solvents, catalysts, energy input) on the yield is discussed. New combinations of reagents enabling the synthesis of a wide range of 3,4-dihydropyrimidin-2(1H)-one derivatives with various functional groups are considered.

引用

页码：413 / 415

页数：3

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