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- [31] A fall in urine protein with combined angiotensin converting enzyme inhibitor (ACEI) and AII receptor antagonist (AIIRA) treatment predicts a good outcome at three years in patients with chronic renal disease (mean serum creatinine level of 0.18 mmols/Litre mean urinary protein level of 2.3 grams/24 hours). Diabetic and obese patients with poor response to combined ACEI and AIIRA treatment have a poor outcome. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2003, 14 : 786A - 786A