What are we missing? Three cases of severe COVID-19 pneumonia with negative testing

被引：1

作者：

Siddiqui, Aisha ^{[1
]}

Singh, Sukhdev ^{[1
]}

Khan, Zohaib ^{[1
]}

Foster, Allison ^{[1
]}

Atere, Muhammed ^{[2
]}

Nfonoyim, Jay M. ^{[3
]}

机构：

[1] Amer Univ Antigua, Coll Med, One Battery Pk Plaza, New York, NY 10004 USA

[2] Richmond Univ, Med Ctr, Dept Internal Med, Staten Isl, NY USA

[3] Richmond Univ, Med Ctr, Staten Isl, NY USA

来源：

SAGE OPEN MEDICAL CASE REPORTS | 2020年 / 8卷

关键词：

Infectious diseases; critical care; emergency medicine; epidemiology; public health; SARS-COV-2; DIAGNOSIS; CT;

D O I：

10.1177/2050313X20965410

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The COVID-19 pandemic has drastically affected health care systems globally. Reverse transcriptase-polymerase chain reaction is currently the preferred method of detecting COVID-19; however, sensitivity of this test remains questionable. Incidental transmission and potential harm to infected individuals are some consequences of the failure to identify high-risk patients. We report three cases of symptomatic patients that required intensive care management with labs and imaging consistent with COVID-19 with initial false-negative reverse transcriptase-polymerase chain reaction testing. Improper sampling, viral load, and manufacturer variances of tests all contribute to reduced sensitivity. A clinical diagnosis should supplant such cases.

引用

页数：5

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