This paper is study aimed to analize on synergy of policy implementation for the development of Small and Medium Enterprises (SMEs) through Corporate Social Responsibility program and strengthening the role of the government agencies in Gorontalo city was a contribution of higher education institution in meeting the current challenges among the community, especially related to the improvement of policy implementation on the development of SMEs. This was a qualitative study which was conducted for a year. The informants for this study were obtained through purposive sampling method, they were comprised of: SMEs groups as beneficiaries of CSR program, field facilitator of the CSR Program, Experts in Public Policy, NGOs, City Office of Cooperation, Industry and Trades, and other related government agencies. The data were collected through observation, interview, and documentation. The data analysis was started from data collection, data reduction, data presentation, and conclusion drawing. In addition, in each stage of the data collections, Focus Group Discussions (FGD) was held with all related stakeholders.