A novel RNA-binding motif in influenza A virus non-structural protein 1

被引：94
|
作者：
Chien, CY
Tejero, R
Huang, YP
Zimmerman, DE
Rios, CB
Krug, RM
Montelione, GT
机构：
[1] RUTGERS STATE UNIV,CTR ADV BIOTECHNOL & MED,PISCATAWAY,NJ 08854
[2] RUTGERS STATE UNIV,DEPT MOL BIOL & BIOCHEM,PISCATAWAY,NJ 08854
[3] UNIV VALENCIA,DEPT QUIM FIS,E-46100 BURJASSOT,VALENCIA,SPAIN
来源：
NATURE STRUCTURAL BIOLOGY | 1997年 / 4卷 / 11期
关键词：
D O I：
10.1038/nsb1197-891
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The solution NMR structure of the RNA-binding domain from influenza virus non-structural protein 1 exhibits a novel dimeric six-helical protein fold, Distributions of basic residues and conserved salt bridges of dimeric NS1(1-73) suggest that the face containing antiparallel helices 2 and 2' forms a novel arginine-rich nucleic acid binding motif.
引用
收藏
页码：891 / 895
页数：5
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