Metal-free Photochemical Atom Transfer Radical Addition (ATRA) of BrCCl3 to Alkenes

被引：16
|
作者：
Nikitas, Nikolaos F. [1 ]
Voutyritsa, Errika [1 ]
Gkizis, Petros L. [1 ]
Kokotos, Christoforos G. [1 ]
机构：
[1] Natl & Kapodistrian Univ Athens, Dept Chem, Organ Chem Lab, Athens 15771, Greece
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2021年 / 2021卷 / 01期
关键词：
Green Chemistry; Photochemistry; Radical reactions; Synthetic methods; LIGHT PHOTOREDOX CATALYSIS; LEWIS-ACID CATALYSIS; C-H ACTIVATION; MERGING PHOTOREDOX; KHARASCH REACTION; ALPHA-ALKYLATION; AQUEOUS-MEDIA; ALDEHYDES; PHOTOCATALYSIS; HYDROACYLATION;
D O I：
10.1002/ejoc.202001387
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A simple, photochemical, and metal-free protocol for the atom transfer radical addition (ATRA) of bromotrichloromethane onto various alkenes is described. Among a range of organic molecules, phenylglyoxylic acid proved to be the most suitable photoinitiator to promote a sustainable process for the addition of bromotrichloromethane to olefins. This photochemical atom transfer radical protocol can be expanded into a wide substrate scope of aliphatic olefins bearing various functional groups, leading to the corresponding products in good to excellent yields.
引用
收藏
页码：96 / 101
页数：6
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