Association of atopy to asthma severity and medication use in children

被引：21
|
作者：
Schwindt, Christina D.
Tjoa, Thomas
Floro, Joshua N.
McLaren, Christine
Delfino, Ralph J.
机构：
[1] Univ Calif Irvine, Univ Childrens Hosp, Dept Pediat, Irvine, CA USA
[2] Univ Calif Irvine, Dept Med, Div Epidemiol, Irvine, CA 92717 USA
来源：
JOURNAL OF ASTHMA | 2006年 / 43卷 / 06期
关键词：
allergens; panel study; epidemiology; severity of illness index; risk factors;
D O I：
10.1080/02770900600758234
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
The importance of aeroallergens as triggers for asthma is well recognized, but the relationship between asthma severity and atopic profiles in childhood has not been elucidated. This study assessed the relationship of allergen sensitization to asthma severity in a study of 114 asthmatic children followed for 8 weeks in three Southern California areas. Increased controller medication and beta-agonist use were positively associated with number of positive skin tests and allergy to mold and pollens. Mold was associated with increased asthma symptoms. Degree of atopy and reactivity to mold and pollens plays a significant role in asthma severity in asthmatic children.
引用
收藏
页码：439 / 446
页数：8
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