Non-coding RNAs in the nervous system

被引:135
|
作者
Mehler, Mark F.
Mattick, John S. [1 ]
机构
[1] Univ Queensland, Inst Mol Biosci, ARC Special Res Ctr Funct & Appl Genomics, St Lucia, Qld 4072, Australia
[2] Yeshiva Univ Albert Einstein Coll Med, Rose F Kennedy Ctr Res Mental Retardat & Dev Disa, Bronx, NY 10461 USA
[3] Yeshiva Univ Albert Einstein Coll Med, Inst Brain Disorders & Neural Regenerat, Albert Einstein Canc Ctr, Dept Psychiat & Behav, Bronx, NY 10461 USA
[4] Yeshiva Univ Albert Einstein Coll Med, Dept Neurol, Albert Einstein Canc Ctr, Inst Brain Disorders & Neural Regenerat, Bronx, NY 10461 USA
[5] Yeshiva Univ Albert Einstein Coll Med, Dept Neurosci, Albert Einstein Canc Ctr, Inst Brain Disorders & Neural Regenerat, Bronx, NY 10461 USA
来源
JOURNAL OF PHYSIOLOGY-LONDON | 2006年 / 575卷 / 02期
关键词
D O I
10.1113/jphysiol.2006.113191
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Increasing evidence suggests that the development and function of the nervous system is heavily dependent on RNA editing and the intricate spatiotemporal expression of a wide repertoire of non-coding RNAs, including micro RNAs, small nucleolar RNAs and longer non-coding RNAs. Non-coding RNAs may provide the key to understanding the multi-tiered links between neural development, nervous system function, and neurological diseases.
引用
收藏
页码:333 / 341
页数:9
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