Noise stochastic corrected maximum a posteriori estimator for birefringence imaging using polarization-sensitive optical coherence tomography

被引:25
|
作者
Kasaragod, Deepa [1 ]
Makita, Shuichi [1 ]
Hong, Young-Joo [1 ]
Yasuno, Yoshiaki [1 ]
机构
[1] Univ Tsukuba, Computat Opt Grp, Tsukuba, Ibaraki, Japan
来源
BIOMEDICAL OPTICS EXPRESS | 2017年 / 8卷 / 02期
基金
日本学术振兴会;
关键词
DEPTH-RESOLVED BIREFRINGENCE; PHASE RETARDATION; ANTERIOR SEGMENT; FIBER LAYER; HUMAN EYE; COLLAGEN; DOPPLER; CORNEA; SKIN;
D O I
10.1364/BOE.8.000653
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
This paper presents a noise-stochastic corrected maximum a posteriori estimator for birefringence imaging using Jones matrix optical coherence tomography. The estimator described in this paper is based on the relationship between probability distribution functions of the measured birefringence and the effective signal to noise ratio (ESNR) as well as the true birefringence and the true ESNR. The Monte Carlo method is used to numerically describe this relationship and adaptive 2D kernel density estimation provides the likelihood for a posteriori estimation of the true birefringence. Improved estimation is shown for the new estimator with stochastic model of ESNR in comparison to the old estimator, both based on the Jones matrix noise model. A comparison with the mean estimator is also done. Numerical simulation validates the superiority of the new estimator. The superior performance of the new estimator was also shown by in vivo measurement of optic nerve head. (C) 2017 Optical Society of America
引用
收藏
页码:653 / 669
页数:17
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