Resin selection for the separation of caffeine from green tea catechins

被引:26
|
作者
Sevillano, David Mendez [1 ]
van der Wielen, Luuk A. M. [1 ]
Hooshyar, Nasim [2 ]
Ottens, Marcel [1 ]
机构
[1] Dept Biotechnol, NL-2628 BC Delft, Netherlands
[2] Unilever Res Labs, NL-3133 AT Vlaardingen, Netherlands
关键词
Green tea; Catechins; Caffeine; Macroporous polymeric resins; High throughput experimentation; Resin selection; SIMULATED MOVING-BED; DIFFUSION-COEFFICIENTS; CHROMATOGRAPHY;
D O I
10.1016/j.fbp.2014.02.002
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
This work focuses on the rapid selection of a resin from a defined set of macroporous polymeric resins for the decaffeination of catechins from green tea. High-throughput experimentation and design of experiments are used in order to retrieve as much information as possible from a small set of experiments on the interaction of components with the resins. A multicomponent Langmuir isotherm model is used to describe the adsorption and parameters are regressed with high accuracy. These parameters are subsequently used for the definition of criteria to calculate a weighted resin score. The optimal resin is Diaion 20HP with a score of 90.50%, mainly due to its good selectivity for caffeine over catechin (3). (C) 2014 The Institution of Chemical Engineers. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:192 / 198
页数:7
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