An Efficient and Recycling Catalyst for the One-Pot Three-Component Synthesis of Substituted 3,4-Dihydropyrimidin-2(1H)-ones

被引：22

作者：

Boumoud, Taoues ^{[1
]}

Boumoud, Boudjemaa ^{[1
]}

Rhouati, Salah ^{[1
]}

Belfaitah, Ali ^{[1
]}

Debache, Abdelmadjid ^{[1
]}

Mosset, Paul ^{[2
]}

机构：

[1] Univ Mentouri Constantine, Fac Sci, Dept Chim, Lab Prod Nat Origine Vegetale & Synth Organ, Constantine 25000, Algeria

[2] ENSCR, CNRS, UMR 6226, F-35700 Rennes, France

来源：

E-JOURNAL OF CHEMISTRY | 2008年 / 5卷 / 04期

关键词：

Biginelli reaction; multi-component reactions (MCRs); Dihydropyrimidinones (DHPMs); Lead(II) nitrate; Scaffold; Leader file;

D O I：

10.1155/2008/132879

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The Biginelli one-pot three-component cyclocondensation was applied in this work to prepare 3,4-dihydropyrimidinone and its analogues using the first derivative of lead, Pb(NO3)(2), as a recycling catalyst, from a diversity of aromatic aldehydes, beta-ketoesters and urea. The reaction was carried out in refluxing acetonitrile and afforded the target molecules in good to excellent yields. The method offers several advantages including high yields of the products, short reaction times and easy experimental workup procedure.

引用

页码：688 / 695

页数：8

共 50 条

[41] Potassium Fluoride-Modified Clay as a Reusable Heterogeneous Catalyst for One-Pot Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones
S. Bentahar
M. Ait Taleb
A. Sabour
A. Dbik
M. El Khomri
N. El Messaoudi
A. Lacherai
R. Mamouni
Russian Journal of Organic Chemistry, 2019, 55 : 1423 - 1431
[42] An efficient and modified biginelli one-pot synthesis of new isoxazole substituted 3,4-dihydropyrimidin-2(1H)-ones and thiones catalyzed by VCl3
Rajanarendar, E.
Ramesh, P.
Mohan, G.
Rao, E. Kalyan
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2007, 44 (02) : 483 - 486
[43] One-pot, multi-component synthesis of 3,4-dihydropyrimidin-2(1H)-one derivatives containing ferrocenyl
Yuting Liu
Yang Dang
Dawei Yin
Xiaoming Yang
Lan Yang
Qian Zou
Research on Chemical Intermediates, 2020, 46 : 547 - 555
[44] One-pot Synthesis of 3,4-Dihydropyrimidin-2(1H)-one Using TsOH as a Catalyst under Microwave Irradiation
屠树江
房芳
缪春宝
蒋虹
史达清
ChineseJournalofChemistry, 2003, (06) : 706 - 709
[45] Unprecedented catalytic three component one-pot condensation reaction: An efficient synthesis of 5-alkoxycarbonyl-4-aryl-3,4-dihydropyrimidin-2(1H)-ones
Hu, EH
Sidler, DR
Dolling, UH
JOURNAL OF ORGANIC CHEMISTRY, 1998, 63 (10): : 3454 - 3457
[46] Experimental and theoretical study on a one-pot, three-component route to 3,4-dihydropyrimidin-2(1H)-ones/thiones TiCl3OTf-[bmim]Cl
Farhadi, Asadollah
Noei, Jalil
Aliyari, Rasoul Haji
Albakhtiyari, Maryam
Takassi, Mohammad Ali
RESEARCH ON CHEMICAL INTERMEDIATES, 2016, 42 (02) : 1401 - 1409
[47] Convenient one-pot heterogeneous catalytic method for the preparation of 3,4-dihydropyrimidin-2(1H)-ones
Hegedüs, A
Hell, Z
Vígh, I
SYNTHETIC COMMUNICATIONS, 2006, 36 (01) : 129 - 136
[48] Experimental and theoretical study on a one-pot, three-component route to 3,4-dihydropyrimidin-2(1H)-ones/thiones TiCl3OTf-[bmim]Cl
Asadollah Farhadi
Jalil Noei
Rasoul Haji Aliyari
Maryam Albakhtiyari
Mohammad Ali Takassi
Research on Chemical Intermediates, 2016, 42 : 1401 - 1409
[49] Ascorbic acid-Catalyzed One-Pot Three-Component Biginelli Reaction: A Practical and Green Approach towards Synthesis of 3,4-dihydropyrimidin-2(1H)-ones/thiones
Sehout, Imene
Boulcina, Raouf
Boumoud, Boudjemaa
Berree, Fabienne
Carboni, Bertrand
Debache, Abdelmadjid
LETTERS IN ORGANIC CHEMISTRY, 2013, 10 (07) : 463 - 467
[50] Bionanostructure-catalyzed one-pot three-component synthesis of 3,4-dihydropyrimidin-2(1H)-one derivatives under solvent-free conditions
Maleki, Ali
Paydar, Reza
REACTIVE & FUNCTIONAL POLYMERS, 2016, 109 : 120 - 124

← 1 2 3 4 5 →