Food allergy and food intolerance: diagnosis and treatment

被引：21

作者：

Patriarca, Giampiero ^{[1
]}

Schiavino, Domenico ^{[1
]}

Pecora, Valentina ^{[1
]}

Lombardo, Carla ^{[1
]}

Pollastrini, Emanuela ^{[1
]}

Aruanno, Arianna ^{[1
]}

Sabato, Vito ^{[1
]}

Colagiovanni, Amira ^{[1
]}

Rizzi, Angela ^{[1
]}

De Pasquale, Tiziana ^{[1
]}

Roncallo, Chiara ^{[1
]}

Decinti, Marzia ^{[1
]}

Musumeci, Sonia ^{[1
]}

Gasbarrini, Giovanni ^{[2
]}

Buonomo, Alessandro ^{[1
]}

Nucera, Eleonora ^{[1
]}

机构：

[1] Catania Univ, Dept Allergol, Policlin A Gemelli, I-00168 Rome, Italy

[2] Catholic Univ, Inst Internal Med, Rome, Italy

来源：

INTERNAL AND EMERGENCY MEDICINE | 2009年 / 4卷 / 01期

关键词：

Food allergy; Food intolerance; Skin prick test; Double-blind placebo controlled food challenge; Oral specific desensitization; ORAL RUSH DESENSITIZATION; COWS MILK ALLERGY; ATOPY PATCH TEST; LATEX ALLERGY; DOUBLE-BLIND; CHRONIC URTICARIA; PREDICTIVE-VALUE; NATURAL-HISTORY; CLINICAL-COURSE; CELIAC-DISEASE;

D O I：

10.1007/s11739-008-0183-6

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Food allergy is a matter of concern because it affects about 0.5-3.8% of the paediatric population and 0.1-1% of adults, and as well may cause life-threatening reactions. Skin prick testing with food extracts and with fresh foods, the measurement of food-specific IgE, elimination diets and a double-blind, placebo-controlled food challenge are the main diagnostic procedures; many non-validated procedures are available, creating confusion among patients and physicians. The treatment of food allergy is still a matter of debate. Antihistamines, corticosteroids and, if necessary (in case of anaphylaxis), epinephrine, are the drugs of choice for the treatment of symptoms of food allergy. Sodium cromolyn may be used prophylactically even though there are no controlled studies certifying its efficacy. The only etiologic treatment of food allergy is specific desensitization. Sublingual-oral-specific desensitization has been used by our group for the treatment of food-allergic patients with a high percentage of success.

引用

页码：11 / 24

页数：14

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