Sugar recognition and protein-protein interaction of mammalian lectins conferring diverse functions

被引：28

作者：

Nagae, Masamichi ^{[1
]}

Yamaguchi, Yoshiki ^{[1
]}

机构：

[1] RIKEN Max Planck Joint Res Ctr, RIKEN Global Res Cluster, Syst Glycobiol Res Grp, Struct Glycobiol Team, Wako, Saitama 3510198, Japan

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 2015年 / 34卷

关键词：

COMPLEX N-GLYCANS; STRUCTURAL-BASIS; PILR-ALPHA; CEL-III; SELECTIVE RECOGNITION; BACTERICIDAL LECTIN; RECEPTOR GALECTIN-8; BINDING PROTEIN; MOLECULAR-BASIS; CROSS-LINKING;

D O I：

10.1016/j.sbi.2015.08.005

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent advances in structural analyses of mammalian lectins reveal atomic-level details of their fine specificities toward diverse endogenous and exogenous glycans. Local variations on a common scaffold can enable certain lectins to recognize complex carbohydrate ligands including branched glycans and O-glycosylated peptides. Simultaneous recognition of both glycan and the aglycon moieties enhances the affinity and specificity of lectins such as CLEC-2 and PILR alpha. Attention has been paid to the roles of galectin and RegIII family of proteins in protein-protein interactions involved in critical biological functions including signal transduction and bactericidal pore formation.

引用

页码：108 / 115

页数：8

共 50 条

[21] A Novel Approach for Protein-Named Entity Recognition and Protein-Protein Interaction Extraction
Li, Meijing
Munkhdalai, Tsendsuren
Yu, Xiuming
Ryu, Keun Ho
MATHEMATICAL PROBLEMS IN ENGINEERING, 2015, 2015
[22] Prediction of protein-protein binding affinity using diverse protein-protein interface features
Guo, Y. (yzguo@scu.edu.cn), 1600, Elsevier B.V. (138):
[23] Hydration and protein-protein interaction
Janin, J
HYDRATION PROCESSES IN BIOLOGY: THEORETICAL AND EXPERIMENTAL APPROACHES, 1999, 305 : 159 - 173
[24] Prediction of protein-protein binding affinity using diverse protein-protein interface features
Ma, Duo
Guo, Yanzhi
Luo, Jiesi
Pu, Xuemei
Li, Menglong
CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS, 2014, 138 : 7 - 13
[25] Prediction of protein-protein binding affinity using diverse protein-protein interface features
Ma, Duo
Guo, Yanzhi
Luo, Jiesi
Pu, Xuemei
Li, Menglong
Chemometrics and Intelligent Laboratory Systems, 2014, 138 : 7 - 13
[26] PROTEIN-PROTEIN INTERACTION IN TRANSPORT
AMES, GF
JOURNAL OF CELLULAR PHYSIOLOGY, 1976, 89 (04) : 543 - 543
[27] Protein-protein interaction probes
Choi, C
SCIENTIST, 2004, 18 (24): : 31 - 31
[28] PocketQuery: protein-protein interaction inhibitor starting points from protein-protein interaction structure
Koes, David Ryan
Camacho, Carlos J.
NUCLEIC ACIDS RESEARCH, 2012, 40 (W1) : W387 - W392
[29] The diverse bilofunctions of LIM domain proteins: determined by subcellular localization and protein-protein interaction
Zheng, Quanhui
Zhao, Yong
BIOLOGY OF THE CELL, 2007, 99 (09) : 489 - 502
[30] Target selectivity of bicoid is dependent on nonconsensus site recognition and protein-protein interaction
Zhao, C
Dave, V
Yang, F
Scarborough, T
Ma, J
MOLECULAR AND CELLULAR BIOLOGY, 2000, 20 (21) : 8112 - 8123

← 1 2 3 4 5 →