Adipokines and adipocyte targets in the future management of obesity and the metabolic syndrome

被引：50
|
作者：
Kralisch, S. [1 ]
Bluher, M. [1 ]
Paschke, R. [1 ]
Stumvoll, M. [1 ]
Fasshauer, M. [1 ]
机构：
[1] Univ Leipzig, Dept Internal Med 3, D-04103 Leipzig, Germany
来源：
MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2007年 / 7卷 / 01期
关键词：
adipokine; diabetes mellitus; insulin resistance; obesity;
D O I：
10.2174/138955707779317821
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The role of adipocytes has been recently better understood. Several adipocytokines have been identified, including leptin, a main regulator of appetite and energy expenditure, adiponectin and others, as novel insulin-sensitizers/insulin-mimetics, and some others inducing insulin resistance. Adipocytokines thus represent interesting novel drug targets in the future management of obesity.
引用
收藏
页码：39 / 45
页数：7
相关论文
共 50 条
  • [31] The Efficacy of Adipokines and Indices of Metabolic Syndrome as Predictors of Severe Obesity-Related Hepatic Steatosis
    Nahum Méndez-Sánchez
    Norberto C. Chávez-Tapia
    Roberto Medina-Santillán
    Antonio R. Villa
    Karla Sánchez-Lara
    Guadalupe Ponciano-Rodríguez
    Martha H. Ramos
    Misael Uribe
    Digestive Diseases and Sciences, 2006, 51
  • [32] The efficacy of adipokines and indices of metabolic syndrome as predictors of severe obesity-related hepatic steatosis
    Mendez-Sanchez, Nahum
    Chavez-Tapia, Norberto C.
    Medina-Santillan, Roberto
    Villa, Antonio R.
    Sanchez-Lara, Karla
    Ponciano-Rodriguez, Guadalupe
    Ramos, Martha H.
    Uribe, Misael
    DIGESTIVE DISEASES AND SCIENCES, 2006, 51 (10) : 1716 - 1722
  • [33] Maternal obesity and programming of metabolic syndrome in the offspring: searching for mechanisms in the adipocyte progenitor pool
    Taylor B. Scheidl
    Amy L. Brightwell
    Sarah H. Easson
    Jennifer A. Thompson
    BMC Medicine, 21
  • [34] Adipokines in metabolic processes regulating during obesity treatment
    Litvinova, L. S.
    Vasilenko, M. A.
    Zatolokin, P. A.
    Aksenova, N. N.
    Vaysbeyn, I. Z.
    Fattakhov, N. S.
    Mironyuk, N.
    DIABETES MELLITUS, 2014, 17 (03): : 51 - 59
  • [35] Maternal obesity and programming of metabolic syndrome in the offspring: searching for mechanisms in the adipocyte progenitor pool
    Scheidl, Taylor B.
    Brightwell, Amy L.
    Easson, Sarah H.
    Thompson, Jennifer A.
    BMC MEDICINE, 2023, 21 (01)
  • [36] Adipocyte morphology and implications for metabolic derangements in obesity
    Heinonen, S.
    Saarinen, L.
    Naukkarinen, J.
    Rodriguez, A.
    Fruehbeck, G.
    Hakkarainen, A.
    Lundbom, J.
    Lundbom, N.
    Arner, P.
    Hautaniemi, S.
    Suomalainen, A.
    Kaprio, J.
    Rissanen, A.
    Pietilainen, K.
    DIABETOLOGIA, 2013, 56 : S311 - S311
  • [37] Obesity, metabolic syndrome and esophageal adenocarcinoma: Epidemiology, etiology and new targets
    Ryan, Aoife M.
    Duong, Michelle
    Healy, Laura
    Ryan, Stephen A.
    Parekh, Niyati
    Reynolds, John V.
    Power, Derek G.
    CANCER EPIDEMIOLOGY, 2011, 35 (04) : 309 - 319
  • [38] The success of sleeve gastrectomy in the management of metabolic syndrome and obesity
    Asim Shabbir
    Dallan Dargan
    TheJournalofBiomedicalResearch, 2015, 29 (02) : 93 - 97
  • [39] The success of sleeve gastrectomy in the management of metabolic syndrome and obesity
    Shabbir, Asim
    Dargan, Dallan
    JOURNAL OF BIOMEDICAL RESEARCH, 2015, 29 (02): : 93 - 97
  • [40] Surgical Management of Metabolic Syndrome Related to Morbid Obesity
    Rehrig, Scott T., Jr.
    PRIMARY CARE, 2016, 43 (01): : 145 - +
12345