Adipokines and adipocyte targets in the future management of obesity and the metabolic syndrome

被引：50
|
作者：
Kralisch, S. [1 ]
Bluher, M. [1 ]
Paschke, R. [1 ]
Stumvoll, M. [1 ]
Fasshauer, M. [1 ]
机构：
[1] Univ Leipzig, Dept Internal Med 3, D-04103 Leipzig, Germany
来源：
MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2007年 / 7卷 / 01期
关键词：
adipokine; diabetes mellitus; insulin resistance; obesity;
D O I：
10.2174/138955707779317821
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The role of adipocytes has been recently better understood. Several adipocytokines have been identified, including leptin, a main regulator of appetite and energy expenditure, adiponectin and others, as novel insulin-sensitizers/insulin-mimetics, and some others inducing insulin resistance. Adipocytokines thus represent interesting novel drug targets in the future management of obesity.
引用
收藏
页码：39 / 45
页数：7
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