Making the Case: Intra-arterial Therapy for Less Common Metastases

被引:9
|
作者
Gordon, Andrew C. [1 ]
Uddin, Omar M. [1 ]
Riaz, Ahsun [1 ]
Salem, Riad [1 ,2 ,3 ]
Lewandowski, Robert J. [1 ,2 ,3 ]
机构
[1] Northwestern Univ, Sect Intervent Radiol, Dept Radiol, Chicago, IL 60611 USA
[2] Northwestern Univ, Dept Med, Div Hematol & Oncol, Chicago, IL 60611 USA
[3] Northwestern Univ, Dept Surg, Div Transplant Surg, Chicago, IL 60611 USA
关键词
hepatic artery infusion chemotherapy; chemoembolization; radioembolization; liver metastases; interventional radiology; HEPATIC ARTERIAL INFUSION; CANCER LIVER METASTASES; SINGLE-CENTER EXPERIENCE; BREAST-CANCER; UVEAL MELANOMA; Y-90; RADIOEMBOLIZATION; PANCREATIC-CANCER; TRANSARTERIAL-CHEMOEMBOLIZATION; SYSTEMIC CHEMOTHERAPY; RETROSPECTIVE ANALYSIS;
D O I
10.1055/s-0037-1601852
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Intra-arterial therapies have high antitumor activity for both primary and secondary hepatic malignancies. Selective infusions allow increased delivery of cytoreductive therapy to the tumor bed while sparing the normal hepatic parenchyma. These therapies are now often applied in the outpatient setting or with short overnight hospital stays and have a growing role in the treatment of liver-dominant disease from metastatic colorectal cancer and from neuroendocrine tumors. Less commonly, intraarterial therapies are applied to treat secondary hepatic malignancies from breast cancer, melanoma, pancreatic adenocarcinoma, and soft-tissue sarcomas. The available data are limited and generally retrospective observational cohort series of single institutions. The purpose of this article is to summarize the recent literature on outcomes for intra-arterial therapy in nonsurgical patients. Multi-institutional registries and prospective data are greatly needed, as intra-arterial therapies are increasingly applied in these patients to stop progression of chemorefractory tumors.
引用
收藏
页码:132 / 139
页数:8
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